Viral OTU vOTU-169560

vOTU: vOTU-169560

Overview

Genome (FASTA) Annotation Track (GFF) Proteins (FASTA) Protein Annotation (TSV)

Cluster Properties
vOTU ID	vOTU-169560
Number of Genomes	1
Taxonomy (ICTV)	root → Duplodnaviria → Heunggongvirae → Uroviricota → Caudoviricetes
Taxonomy (UHGV)	vFAM-00006 → vSUBFAM-01156 → vOTU-169560
Host Lineage	Bacteria → Firmicutes_A → Clostridia → Lachnospirales → Lachnospiraceae → Roseburia → Roseburia inulinivorans
Viral Lifestyle	temperate

Representative Genome
Genome ID	UHGV-2191254
Biosample ID	N/A
Length	28,519 bps
CheckV Completeness	68.00% (Medium-quality)
CDS Count	55
CDS Density	93.82%
tRNA Count	0
Viral Confidence	Confident

Representative Genome Content

Select to view: Genome Viewer Functional Annotation

Genome View (Completeness: 68)

Functional Annotation

Reference	Gene ID	Reference ID	Bit-score	E-value	Information	Category
PHROG	UHGV-2191254_2	phrog_87	71.6	9.1e-21	metallo-protease	other
UniRef90	UHGV-2191254_2	UniRef90_A0A3R6K8Y6	236.0	0	Peptidase_M78 domain-containing protein	N/A
eggNOG-mapper	UHGV-2191254_2	553973.CLOHYLEM_07298	173.0	0	IrrE N-terminal-like domain	N/A
COG	UHGV-2191254_2	COG2856	N/A	N/A	Zn-dependent peptidase ImmA, M78 family	N/A
structural_annotation	UHGV-2191254_2	PF06114,COG2856	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_3	K22299	43.9	0.0000000000045	rghR; HTH-type transcriptional regulator, competence development regulator	N/A
PHROG	UHGV-2191254_3	phrog_8	53.3	0.0000000000000061	transcriptional regulator	transcription regulation
UniRef90	UHGV-2191254_3	UniRef90_R5ZAU1	109.0	6.82e-28	Conserved domain protein	N/A
eggNOG-mapper	UHGV-2191254_3	1123511.KB905868_gene209	81.3	3.72e-17	Helix-turn-helix XRE-family like proteins	N/A
Pfam	UHGV-2191254_3	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
COG	UHGV-2191254_3	COG1396	N/A	N/A	Transcriptional regulator, contains XRE-family HTH domain	N/A
structural_annotation	UHGV-2191254_3	PF01381,MF_02017,NF007257,COG1396	N/A	N/A	N/A	N/A
UniRef90	UHGV-2191254_4	UniRef90_UPI000E52936A	102.0	9.94e-27	helix-turn-helix domain-containing protein	N/A
eggNOG-mapper	UHGV-2191254_4	887929.HMP0721_1290	85.1	7.74e-21	Helix-turn-helix domain of resolvase	N/A
Pfam	UHGV-2191254_4	PF13443	N/A	N/A	Cro/C1-type HTH DNA-binding domain	HTH_26
structural_annotation	UHGV-2191254_4	PF05339,NF041951,COG3655	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_5	K07741	140.9	1.70006e-41	antB; anti-repressor protein	N/A
PHROG	UHGV-2191254_5	phrog_63	117.8	1.1e-34	anti-repressor Ant	transcription regulation
UniRef90	UHGV-2191254_5	UniRef90_A0A373CW16	441.0	0	Phage antirepressor Ant	N/A
eggNOG-mapper	UHGV-2191254_5	411470.RUMGNA_02184	296.0	0	Phage antirepressor protein	N/A
Pfam	UHGV-2191254_5	PF08346	N/A	N/A	AntA/AntB antirepressor	AntA
Pfam	UHGV-2191254_5	PF03374	N/A	N/A	Phage antirepressor protein KilAC domain	ANT
COG	UHGV-2191254_5	COG3561	N/A	N/A	Phage anti-repressor protein Ant	N/A
structural_annotation	UHGV-2191254_5	PF03374,PF08346,TIGR02681,COG3561,COG3645	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_6	phrog_6058	41.5	0.000000000017	N/A	unknown function
structural_annotation	UHGV-2191254_7	PF11127	N/A	N/A	N/A	N/A
structural_annotation	UHGV-2191254_9	PF15513,NF007469	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_11	K03698	53.1	0.0000000000000046	cbf, cbf1; 3'-5' exoribonuclease [EC:3.1.-.-]	N/A
PHROG	UHGV-2191254_11	phrog_5889	106.0	2.3e-31	N/A	unknown function
UniRef90	UHGV-2191254_11	UniRef90_A0A3R5ZBU3	380.0	0	HD family phosphohydrolase	N/A
eggNOG-mapper	UHGV-2191254_11	411468.CLOSCI_00316	218.0	0	Metal dependent phosphohydrolases with conserved 'HD' motif.	N/A
Pfam	UHGV-2191254_11	PF01966	N/A	N/A	HD domain	HD
COG	UHGV-2191254_11	COG3481	N/A	N/A	3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation, HD superfamily	N/A
structural_annotation	UHGV-2191254_11	PF07514,MF_01427,NF010007,COG3481	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_12	phrog_14970	246.5	0	N/A	unknown function
UniRef90	UHGV-2191254_12	UniRef90_UPI00123F00F5	194.0	0	Rad52/Rad22 family DNA repair protein	N/A
eggNOG-mapper	UHGV-2191254_12	1410632.JHWW01000001_gene1266	193.0	0	double-strand break repair protein	N/A
Pfam	UHGV-2191254_12	PF04098	N/A	N/A	Rad52/22 family double-strand break repair protein	Rad52_Rad22
COG	UHGV-2191254_12	COG4712	N/A	N/A	Predicted ssDNA annealing protein, contains HHH motif, Rad42/Rad22/RecT/erf family	N/A
structural_annotation	UHGV-2191254_12	PF04098,TIGR00607,COG4712	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_13	phrog_398	216.7	0	N/A	unknown function
UniRef90	UHGV-2191254_13	UniRef90_UPI001E5E0390	295.0	0	putative HNHc nuclease	N/A
eggNOG-mapper	UHGV-2191254_13	33035.JPJF01000122_gene2462	289.0	0	Putative HNHc nuclease	N/A
Pfam	UHGV-2191254_13	PF16784	N/A	N/A	Putative HNHc nuclease	HNHc_6
structural_annotation	UHGV-2191254_13	PF16784	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_14	K01160	42.3	0.000000000019	rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]	N/A
PHROG	UHGV-2191254_14	phrog_1682	75.1	9.8e-22	RusA-like Holliday junction resolvase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-2191254_14	UniRef90_A0A412FH46	252.0	0	RusA family crossover junction endodeoxyribonuclease	N/A
eggNOG-mapper	UHGV-2191254_14	1235790.C805_00029	164.0	0	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC	N/A
Pfam	UHGV-2191254_14	PF05866	N/A	N/A	Endodeoxyribonuclease RusA	RusA
COG	UHGV-2191254_14	COG4570	N/A	N/A	Holliday junction resolvase RusA (prophage-encoded endonuclease)	N/A
structural_annotation	UHGV-2191254_14	PF19595,NF007305,COG4570	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_15	phrog_19658	45.1	0.00000000000088	replication initiation protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-2191254_15	UniRef90_UPI001626ADE8	117.0	3.24e-28	DnaD domain protein	N/A
eggNOG-mapper	UHGV-2191254_15	1071400.LBUCD034_0926	114.0	2.9e-27	DnaD domain protein	N/A
COG	UHGV-2191254_15	COG3935	N/A	N/A	DNA replication protein DnaD	N/A
structural_annotation	UHGV-2191254_15	PF10771,MF_01177,TIGR01714,COG5529	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_16	K02315	148.3	5.88545e-44	dnaC; DNA replication protein DnaC	N/A
PHROG	UHGV-2191254_16	phrog_50	146.7	1.69557e-43	DnaC-like helicase loader	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-2191254_16	UniRef90_A0A1Q6KIH9	461.0	0	IstB_IS21 domain-containing protein	N/A
eggNOG-mapper	UHGV-2191254_16	742733.HMPREF9469_01844	235.0	0	IstB-like ATP binding protein	N/A
Pfam	UHGV-2191254_16	PF01695	N/A	N/A	IstB-like ATP binding protein	IstB_IS21
COG	UHGV-2191254_16	COG1484	N/A	N/A	DNA replication protein DnaC	N/A
structural_annotation	UHGV-2191254_16	PF01695,MF_00377,NF005992,COG1484	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_20	phrog_37916	85.1	5e-25	N/A	unknown function
UniRef90	UHGV-2191254_21	UniRef90_UPI001D072F7E	69.7	0.0000000000198	N/A	N/A
eggNOG-mapper	UHGV-2191254_21	397290.C810_01492	54.3	0.000000956	N/A	N/A
PHROG	UHGV-2191254_22	phrog_8684	96.9	1.5e-28	N/A	unknown function
UniRef90	UHGV-2191254_22	UniRef90_A0A6L6XDP0	204.0	0	YopX domain-containing protein	N/A
eggNOG-mapper	UHGV-2191254_22	397290.C810_01526	77.4	2.21e-16	YopX protein	N/A
Pfam	UHGV-2191254_22	PF09643	N/A	N/A	YopX protein	YopX
NCBIFam	UHGV-2191254_22	TIGR01671.1	N/A	N/A	phage conserved hypothetical protein TIGR01671	N/A
structural_annotation	UHGV-2191254_22	PF09643,TIGR01671	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_24	phrog_599	51.6	0.000000000000019	Lar-like restriction alleviation protein	moron, auxiliary metabolic gene and host takeover
UniRef90	UHGV-2191254_24	UniRef90_A0A3R6D3K6	70.5	0.0000000000000239	Restriction alleviation protein, Lar family	N/A
Pfam	UHGV-2191254_24	PF14354	N/A	N/A	Restriction alleviation protein Lar	Lar_restr_allev
dbAPIS	UHGV-2191254_24	APIS033	N/A	N/A	Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin.	N/A
structural_annotation	UHGV-2191254_24	PF14354,TIGR03655	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_26	phrog_874	158.7	0	N/A	unknown function
UniRef90	UHGV-2191254_26	UniRef90_A0A4P6LRJ9	177.0	0	ASCH domain-containing protein	N/A
eggNOG-mapper	UHGV-2191254_26	411468.CLOSCI_00298	175.0	0	N/A	N/A
structural_annotation	UHGV-2191254_26	PF04266,MF_00684,NF003443,COG4405	N/A	N/A	N/A	N/A
UniRef90	UHGV-2191254_27	UniRef90_UPI001C01D3C5	543.0	0	N/A	N/A
eggNOG-mapper	UHGV-2191254_27	622312.ROSEINA2194_04464	473.0	0	N/A	N/A
Pfam	UHGV-2191254_27	PF14199	N/A	N/A	N/A	DUF4317
structural_annotation	UHGV-2191254_27	PF14199,MF_00730,NF001557,COG3081	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_28	phrog_424	74.5	1.3e-21	phosphoadenosine phosphosulfate reductase	moron, auxiliary metabolic gene and host takeover
UniRef90	UHGV-2191254_28	UniRef90_A0A2H4JC51	434.0	0	Putative 3'-phosphoadenosine 5'-phosphosulfatesulfotransferase/FAD synthetase-related enzyme	N/A
eggNOG-mapper	UHGV-2191254_28	693746.OBV_43240	537.0	0	N/A	N/A
COG	UHGV-2191254_28	COG0175	N/A	N/A	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	N/A
structural_annotation	UHGV-2191254_28	PF01507,MF_00064,TIGR00434,COG0175	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_33	phrog_1672	45.8	0.00000000000073	N/A	unknown function
KOfam	UHGV-2191254_34	K07451	40.6	0.000000000041	mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]	N/A
PHROG	UHGV-2191254_34	phrog_2118	117.6	1.1e-34	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-2191254_34	UniRef90_A0A3R6HC40	244.0	0	HNH endonuclease	N/A
eggNOG-mapper	UHGV-2191254_34	742740.HMPREF9474_03129	236.0	0	HNH endonuclease	N/A
Pfam	UHGV-2191254_34	PF01844	N/A	N/A	HNH endonuclease	HNH
COG	UHGV-2191254_34	COG1403	N/A	N/A	5-methylcytosine-specific restriction endonuclease McrA	N/A
structural_annotation	UHGV-2191254_34	TIGR02646,COG1403	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_39	K01356	44.6	0.0000000000031	lexA; repressor LexA [EC:3.4.21.88]	N/A
UniRef90	UHGV-2191254_39	UniRef90_A0A0F0C7S4	102.0	1.33e-26	LexA repressor	N/A
eggNOG-mapper	UHGV-2191254_39	1235799.C818_03301	65.5	0.000000000000403	LexA DNA binding domain	N/A
Pfam	UHGV-2191254_39	PF01726	N/A	N/A	LexA DNA binding domain	LexA_DNA_bind
COG	UHGV-2191254_39	COG1974	N/A	N/A	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	N/A
structural_annotation	UHGV-2191254_39	PF01726,MF_00732,NF006812,COG3388	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_40	K04763	159.0	0	xerD; integrase/recombinase XerD	N/A
PHROG	UHGV-2191254_40	phrog_1	137.7	1.10001e-40	integrase	integration and excision
UniRef90	UHGV-2191254_40	UniRef90_UPI001C034698	630.0	0	tyrosine-type recombinase/integrase	N/A
eggNOG-mapper	UHGV-2191254_40	45361.MCJ_004130	117.0	2.01e-27	Phage integrase, N-terminal SAM-like domain	N/A
Pfam	UHGV-2191254_40	PF13495	N/A	N/A	Phage integrase, N-terminal SAM-like domain	Phage_int_SAM_4
Pfam	UHGV-2191254_40	PF00589	N/A	N/A	Phage integrase family	Phage_integrase
COG	UHGV-2191254_40	COG4974	N/A	N/A	Site-specific recombinase XerD	N/A
structural_annotation	UHGV-2191254_40	PF00589,PF02899,MF_01807,TIGR02224,COG4973	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_41	K04763	110.5	2.2e-32	xerD; integrase/recombinase XerD	N/A
PHROG	UHGV-2191254_41	phrog_216	163.6	0	integrase	integration and excision
UniRef90	UHGV-2191254_41	UniRef90_UPI001C01F562	369.0	0	tyrosine-type recombinase/integrase	N/A
eggNOG-mapper	UHGV-2191254_41	1235793.C809_02656	203.0	0	PFAM Phage integrase family	N/A
Pfam	UHGV-2191254_41	PF00589	N/A	N/A	Phage integrase family	Phage_integrase
COG	UHGV-2191254_41	COG0582	N/A	N/A	Integrase/recombinase, includes phage integrase	N/A
structural_annotation	UHGV-2191254_41	PF00589,MF_02055,NF040815,COG4973	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_43	phrog_119	49.6	0.00000000000005	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-2191254_43	UniRef90_A0A412EM28	172.0	0	HNH endonuclease	N/A
eggNOG-mapper	UHGV-2191254_43	768710.DesyoDRAFT_1275	94.0	1.15e-22	HNH nucleases	N/A
COG	UHGV-2191254_43	COG1403	N/A	N/A	5-methylcytosine-specific restriction endonuclease McrA	N/A
PHROG	UHGV-2191254_44	phrog_5110	112.6	1.5e-33	terminase small subunit	head and packaging
UniRef90	UHGV-2191254_44	UniRef90_A0A0G3WGQ0	110.0	3.47e-29	Phage terminase, small subunit	N/A
eggNOG-mapper	UHGV-2191254_44	349161.Dred_2608	94.7	1.03e-23	N/A	N/A
Pfam	UHGV-2191254_44	PF05119	N/A	N/A	Phage terminase, small subunit	Terminase_4
structural_annotation	UHGV-2191254_44	PF05119,TIGR01558,COG3747	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_45	phrog_9	264.9	0	terminase large subunit	head and packaging
UniRef90	UHGV-2191254_45	UniRef90_A0A412EM51	868.0	0	Terminase large subunit	N/A
eggNOG-mapper	UHGV-2191254_45	610130.Closa_0741	787.0	0	Phage Terminase	N/A
Pfam	UHGV-2191254_45	PF03354	N/A	N/A	Terminase large subunit, ATPase domain	TerL_ATPase
Pfam	UHGV-2191254_45	PF20441	N/A	N/A	Terminase large subunit, endonuclease domain	TerL_nuclease
COG	UHGV-2191254_45	COG4626	N/A	N/A	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	N/A
structural_annotation	UHGV-2191254_45	PF20441,PF03354,MF_04146,TIGR01547,COG4626	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_46	phrog_12	83.1	1.8e-24	portal protein	head and packaging
UniRef90	UHGV-2191254_46	UniRef90_A0A173RYU7	476.0	0	Phage portal protein, HK97 family	N/A
eggNOG-mapper	UHGV-2191254_46	349161.Dred_2606	196.0	0	Phage portal protein, HK97 family	N/A
Pfam	UHGV-2191254_46	PF04860	N/A	N/A	Phage portal protein	Phage_portal
NCBIFam	UHGV-2191254_46	TIGR01537.1	N/A	N/A	phage portal protein	N/A
COG	UHGV-2191254_46	COG4695	N/A	N/A	Phage portal protein BeeE	N/A
structural_annotation	UHGV-2191254_46	PF04860,MF_04135,TIGR01537,COG4695	N/A	N/A	N/A	N/A
KOfam	UHGV-2191254_47	K01358	98.5	9.4e-29	clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]	N/A
PHROG	UHGV-2191254_47	phrog_94	187.5	0	head maturation protease	head and packaging
UniRef90	UHGV-2191254_47	UniRef90_A0A6N7Y0D2	242.0	0	ATP-dependent Clp protease proteolytic subunit	N/A
eggNOG-mapper	UHGV-2191254_47	1235792.C808_00085	212.0	0	Clp protease	N/A
Pfam	UHGV-2191254_47	PF00574	N/A	N/A	Clp protease	CLP_protease
COG	UHGV-2191254_47	COG0740	N/A	N/A	ATP-dependent protease ClpP, protease subunit	N/A
structural_annotation	UHGV-2191254_47	PF00574,MF_00444,NF011090,COG0740	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_48	phrog_10	90.5	2.1e-26	major head protein	head and packaging
UniRef90	UHGV-2191254_48	UniRef90_A0A173S099	476.0	0	Predicted phage phi-C31 gp36 major capsid-like protein	N/A
eggNOG-mapper	UHGV-2191254_48	1211817.CCAT010000053_gene2132	317.0	0	Phage capsid family	N/A
Pfam	UHGV-2191254_48	PF05065	N/A	N/A	Phage capsid family	Phage_capsid
NCBIFam	UHGV-2191254_48	TIGR01554.2	N/A	N/A	phage major capsid protein	N/A
COG	UHGV-2191254_48	COG4653	N/A	N/A	Predicted phage phi-C31 gp36 major capsid-like protein	N/A
structural_annotation	UHGV-2191254_48	PF05065,MF_04119,TIGR01554,COG4653	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_49	phrog_749	64.0	1.7e-18	N/A	unknown function
UniRef90	UHGV-2191254_49	UniRef90_W0FM58	80.9	1.93e-17	Gp6 protein	N/A
eggNOG-mapper	UHGV-2191254_49	926561.KB900622_gene644	59.7	0.000000000351	N/A	N/A
structural_annotation	UHGV-2191254_49	PF05135,TIGR01560	N/A	N/A	N/A	N/A
UniRef90	UHGV-2191254_50	UniRef90_UPI0011070497	77.4	1.42e-16	phage head closure protein	N/A
structural_annotation	UHGV-2191254_51	PF05657,COG3167	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_52	phrog_5509	82.1	2.8e-24	neck protein	connector
UniRef90	UHGV-2191254_52	UniRef90_W0FMR6	79.7	1.95e-16	Gp9 protein	N/A
eggNOG-mapper	UHGV-2191254_52	1347392.CCEZ01000045_gene11	62.4	0.000000000178	N/A	N/A
structural_annotation	UHGV-2191254_52	TIGR01725,COG5005	N/A	N/A	N/A	N/A
UniRef90	UHGV-2191254_53	UniRef90_A0A316S919	152.0	3.74147e-43	Phage tail protein	N/A
eggNOG-mapper	UHGV-2191254_53	1384484.AEQU_1175	139.0	2.8e-39	N/A	N/A
structural_annotation	UHGV-2191254_53	PF04630,TIGR01603,COG5437	N/A	N/A	N/A	N/A
PHROG	UHGV-2191254_54	phrog_2724	44.0	0.0000000000039	N/A	unknown function
Pfam	UHGV-2191254_54	PF07498	N/A	N/A	Rho termination factor, N-terminal domain	Rho_N
COG	UHGV-2191254_54	COG0261	N/A	N/A	Ribosomal protein L21	N/A
eggNOG-mapper	UHGV-2191254_55	1121866.AUGK01000006_gene886	79.7	9.01e-18	N/A	N/A

All Viral Genomes

ID	Representative?	Length (bps)	% GC Content	CheckV Completeness	geNomad Score
UHGV-2191254	Yes	28,519	38	68	1