UHGV-0021653 (vOTU-043308)

Viral Genome: UHGV-0021653

Genome Information

Genome (FASTA) Annotation track (GFF) Proteins (FASTA) Protein annotation (TSV)

Overview
UHGV ID	UHGV-0021653
vOTU ID	vOTU-043308
Representative Genome?	Yes
Source	Hadza
Original genome ID	Hadza_MoBio_hadza-I-L_B_15_2660__NODE_71_length_179755_cov_22.073754
Associated BioSample	N/A
Viral genome confidence	Confident

Quality assessment
CheckV method	DTR
CheckV completeness	100 (Complete)
Trimmed provirus	No
CheckV viral markers	31
CheckV host markers	3
Recoded stop codon	Yes

Viral Content
geNomad score	0.9743
Virus hallmark genes (geNomad)	11
Plasmid hallmark genes (geNomad)	0
viralVerify prediction	Virus
viralVerify score	41.09
Jumbo phage	No

Genome content
Genome length (bp)	179,678
GC content	32.97%
Genetic code	Blepharisma Nuclear Code (15)
CDS genes	246
CDS density	88%
Average CDS length (bps)	639.43
Total tRNA genes	11
Suppressor tRNA genes	1

Genome content

Select to view: Genome Viewer Functional Annotation

Genome View (Completeness: 100)

Functional Annotation

Reference	Gene ID	Reference ID	Bit-score	E-value	Information	Category
eggNOG-mapper	UHGV-0021653_1	1151292.QEW_3594	52.0	0.000000978	Acetyltransferase (GNAT) domain	N/A
Pfam	UHGV-0021653_1	PF13508	N/A	N/A	Acetyltransferase (GNAT) domain	Acetyltransf_7
COG	UHGV-0021653_1	COG0454	N/A	N/A	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	N/A
structural_annotation	UHGV-0021653_3	PF17981	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_4	K03086	318.3	0	rpoD; RNA polymerase primary sigma factor	N/A
PHROG	UHGV-0021653_4	phrog_351	234.2	0	RNA polymerase sigma factor	transcription regulation
UniRef90	UHGV-0021653_4	UniRef90_R6PP23	231.0	0	RNA polymerase sigma factor SigA	N/A
eggNOG-mapper	UHGV-0021653_4	1105031.HMPREF1141_1760	224.0	0	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	N/A
PADLOC	UHGV-0021653_4	MzaA_00001	161.5	0	NA	mzaABCDE
Pfam	UHGV-0021653_4	PF00140	N/A	N/A	Sigma-70 factor, region 1.2	Sigma70_r1_2
Pfam	UHGV-0021653_4	PF04542	N/A	N/A	Sigma-70 region 2	Sigma70_r2
Pfam	UHGV-0021653_4	PF04539	N/A	N/A	Sigma-70 region 3	Sigma70_r3
Pfam	UHGV-0021653_4	PF04545	N/A	N/A	Sigma-70, region 4	Sigma70_r4
NCBIFam	UHGV-0021653_4	TIGR02937.1	N/A	N/A	sigma-70 family RNA polymerase sigma factor	N/A
COG	UHGV-0021653_4	COG0568	N/A	N/A	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	N/A
structural_annotation	UHGV-0021653_4	PF04542,PF04539,MF_00959,NF005920,COG0568	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_10	K04087	70.6	1.2e-20	hflC; modulator of FtsH protease HflC	N/A
PHROG	UHGV-0021653_10	phrog_200	127.7	6e-38	lipoprotein	other
UniRef90	UHGV-0021653_10	UniRef90_A0A354MAD5	243.0	0	PHB domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_10	511680.BUTYVIB_00242	175.0	0	SPFH domain Band 7 family	N/A
Pfam	UHGV-0021653_10	PF01145	N/A	N/A	SPFH domain / Band 7 family	Band_7
COG	UHGV-0021653_10	COG0330	N/A	N/A	Regulator of protease activity HflC, stomatin/prohibitin superfamily	N/A
structural_annotation	UHGV-0021653_10	PF01145,MF_01562,NF008181,COG0330	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_13	phrog_2310	56.8	2e-16	N/A	unknown function
eggNOG-mapper	UHGV-0021653_13	1151292.QEW_3251	52.0	0.0000000193	N/A	N/A
PHROG	UHGV-0021653_14	phrog_2295	79.5	2.9e-24	N/A	unknown function
Pfam	UHGV-0021653_14	PF21722	N/A	N/A	Glycine-rich domain	Gly_rich_2
structural_annotation	UHGV-0021653_18	PF07210,PF01404,TIGR03000,NF038128,COG2512	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_25	PF04182,MF_01586,NF040939,COG0735	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_27	PF01978,MF_01177,NF008240,COG0735	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_28	phrog_388	48.3	0.00000000000011	nucleotidyltransferase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_28	UniRef90_A0A843FSU3	72.4	0.0000000000234	Nucleotidyltransferase domain-containing protein	N/A
structural_annotation	UHGV-0021653_28	PF10127,NF000079,COG3541	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_31	NF003076,COG0231	N/A	N/A	N/A	N/A
UniRef90	UHGV-0021653_32	UniRef90_UPI001C3F0691	91.7	1.7e-18	methyltransferase domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_32	1410670.JHXF01000020_gene2234	114.0	9.29e-28	N/A	N/A
structural_annotation	UHGV-0021653_32	PF05891,MF_00472,NF005379,COG2227	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_43	phrog_1479	59.3	6e-17	N/A	unknown function
eggNOG-mapper	UHGV-0021653_43	1256908.HMPREF0373_01589	63.9	0.00000000000717	N/A	N/A
Pfam	UHGV-0021653_43	PF20274	N/A	N/A	Cyclic-phosphate processing Receiver domain	cREC_REC
structural_annotation	UHGV-0021653_43	PF20274	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_48	phrog_1649	55.5	6.6e-16	metallo-phosphoesterase	other
UniRef90	UHGV-0021653_48	UniRef90_A0A843FHD5	195.0	0	Metallophosphoesterase	N/A
eggNOG-mapper	UHGV-0021653_48	411489.CLOL250_01479	159.0	4.2039e-45	Calcineurin-like phosphoesterase	N/A
Pfam	UHGV-0021653_48	PF00149	N/A	N/A	Calcineurin-like phosphoesterase	Metallophos
COG	UHGV-0021653_48	COG1408	N/A	N/A	Predicted phosphohydrolase, MPP superfamily	N/A
structural_annotation	UHGV-0021653_48	COG2129	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_57	phrog_547	72.0	5.8e-21	phosphoesterase	other
UniRef90	UHGV-0021653_57	UniRef90_A0A1G6A2L6	134.0	1.69e-36	Calcineurin-like phosphoesterase superfamily protein	N/A
eggNOG-mapper	UHGV-0021653_57	1280668.ATVT01000006_gene1405	142.0	1.61e-37	nucleotidyltransferase activity	N/A
Pfam	UHGV-0021653_57	PF00149	N/A	N/A	Calcineurin-like phosphoesterase	Metallophos
COG	UHGV-0021653_57	COG4186	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_57	MF_00575,TIGR04123,COG4186	N/A	N/A	N/A	N/A
NCBIFam	UHGV-0021653_59	TIGR04429.1	N/A	N/A	Phr family secreted Rap phosphatase inhibitor	N/A
KOfam	UHGV-0021653_63	K02342	52.1	0.0000000000000077	dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]	N/A
PHROG	UHGV-0021653_63	phrog_192	57.4	1.9e-16	DNA polymerase exonuclease subunit	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_63	UniRef90_A0A3D2HTE5	145.0	1.45e-38	Exonuclease domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_63	1121346.KB899811_gene1674	59.3	0.000000184	EXOIII	N/A
PADLOC	UHGV-0021653_63	cd06127	48.2	0.00000000000036	CAS-I,CAS-II,CAS-III,CAS-IV,CAS-V,CAS-VI; associated	CRISPR-CAS
Pfam	UHGV-0021653_63	PF00929	N/A	N/A	Exonuclease	RNase_T
COG	UHGV-0021653_63	COG0847	N/A	N/A	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	N/A
structural_annotation	UHGV-0021653_63	PF00929,MF_00977,NF005838,COG5018	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_65	phrog_968	191.2	0	RNA ligase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_65	UniRef90_D3E2W5	389.0	0	RNA ligase DRB0094 family	N/A
eggNOG-mapper	UHGV-0021653_65	223192.XP_007918367.1	108.0	2.85e-23	RNA ligase	N/A
Pfam	UHGV-0021653_65	PF21189	N/A	N/A	PHA02142 OB-fold domain	PHA02142
Pfam	UHGV-0021653_65	PF09414	N/A	N/A	RNA ligase	RNA_ligase
structural_annotation	UHGV-0021653_65	PF21189,PF09511,MF_04150,TIGR02306,COG1423,COG0073	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_67	PF11180	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_71	phrog_28997	67.2	1.6e-19	N/A	unknown function
PHROG	UHGV-0021653_73	phrog_16999	117.7	5.7e-35	Fe-S oxidoreductase	other
UniRef90	UHGV-0021653_73	UniRef90_A0A3R6NWH5	297.0	0	Radical SAM protein	N/A
eggNOG-mapper	UHGV-0021653_73	1235802.C823_04702	279.0	0	radical SAM domain protein	N/A
COG	UHGV-0021653_73	COG0535	N/A	N/A	Radical SAM superfamily maturase, SkfB/NifB/PqqE family	N/A
structural_annotation	UHGV-0021653_73	PF00290,MF_00660,TIGR04053,COG0535	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_77	K09117	48.6	0.00000000000013	N/A	N/A
UniRef90	UHGV-0021653_77	UniRef90_R7I2W6	80.9	1.24e-16	YqeY-like protein	N/A
eggNOG-mapper	UHGV-0021653_77	537007.BLAHAN_05390	55.8	0.0000000921	N/A	N/A
Pfam	UHGV-0021653_77	PF09424	N/A	N/A	Yqey-like protein	YqeY
COG	UHGV-0021653_77	COG1610	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_77	PF09424,COG1610	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_78	PF17516,TIGR00739	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_79	phrog_2971	228.8	0	N/A	unknown function
UniRef90	UHGV-0021653_79	UniRef90_UPI00164B073B	291.0	0	VWA domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_79	1392493.JIAB01000001_gene1822	250.0	0	N/A	N/A
structural_annotation	UHGV-0021653_79	PF00092,MF_01340,NF003711,COG4867	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_80	NF041910	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_82	K01939	112.1	4.2e-33	purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4]	N/A
PHROG	UHGV-0021653_82	phrog_1211	143.3	1.3999e-42	adenylosuccinate synthetase	moron, auxiliary metabolic gene and host takeover
UniRef90	UHGV-0021653_82	UniRef90_UPI001ADD8613	225.0	0	adenylosuccinate synthetase	N/A
eggNOG-mapper	UHGV-0021653_82	180332.JTGN01000003_gene2162	224.0	0	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	N/A
Pfam	UHGV-0021653_82	PF00709	N/A	N/A	Adenylosuccinate synthetase	Adenylsucc_synt
COG	UHGV-0021653_82	COG0104	N/A	N/A	Adenylosuccinate synthase	N/A
structural_annotation	UHGV-0021653_82	PF00709,MF_00011,NF010355,COG0104	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0021653_83	1538644.KO02_09795	50.1	0.00000095	N/A	N/A
PHROG	UHGV-0021653_85	phrog_505	63.8	2.7e-18	polynucleotide kinase	other
eggNOG-mapper	UHGV-0021653_85	4787.PITG_05651T0	52.4	0.00000713	AAA domain	N/A
Pfam	UHGV-0021653_85	PF13671	N/A	N/A	AAA domain	AAA_33
COG	UHGV-0021653_85	COG4088	N/A	N/A	tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein)	N/A
structural_annotation	UHGV-0021653_85	PF13671,MF_03172,TIGR03574,COG4639	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0021653_87	1392491.JIAE01000001_gene1129	91.3	5.31e-22	Calcineurin-like phosphoesterase	N/A
COG	UHGV-0021653_87	COG4186	N/A	N/A	N/A	N/A
UniRef90	UHGV-0021653_91	UniRef90_A0A345BPS5	79.0	0.000000000000129	Putative protease	N/A
structural_annotation	UHGV-0021653_91	PF02581,MF_02232,TIGR01182,COG0135	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_92	K01258	50.4	4.4e-22	pepT; tripeptide aminopeptidase [EC:3.4.11.4]	N/A
PHROG	UHGV-0021653_92	phrog_34186	104.9	7.1e-31	N/A	unknown function
UniRef90	UHGV-0021653_92	UniRef90_A0A843FCH3	173.0	0	M28 family peptidase	N/A
eggNOG-mapper	UHGV-0021653_92	935948.KE386495_gene2240	144.0	3.2e-38	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	N/A
Pfam	UHGV-0021653_92	PF04389	N/A	N/A	Peptidase family M28	Peptidase_M28
COG	UHGV-0021653_92	COG0624	N/A	N/A	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	N/A
structural_annotation	UHGV-0021653_92	PF05343,MF_01120,TIGR01883,COG1363	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_94	phrog_5172	124.8	9.5e-38	N/A	unknown function
UniRef90	UHGV-0021653_94	UniRef90_A0A1X9SYG3	240.0	0	DNA methyltransferase	N/A
eggNOG-mapper	UHGV-0021653_94	1345592.CBOM010000007_gene776	179.0	0	DNA restriction-modification system	N/A
PADLOC	UHGV-0021653_94	MTase_II_00060	174.6	0	Type II methyltransferase	RM
COG	UHGV-0021653_94	COG0827	N/A	N/A	Adenine-specific DNA N6-methylase	N/A
structural_annotation	UHGV-0021653_94	PF02384,MF_03044,NF012222,COG2263	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_97	PF13876	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_98	phrog_7168	100.4	1.6e-29	homing endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_98	UniRef90_A0A349YKA3	176.0	0	GIY-YIG domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_98	1345695.CLSA_c35600	82.8	1.16e-16	GIY-YIG type nucleases (URI domain)	N/A
PADLOC	UHGV-0021653_98	HEase_00030	43.2	0.000000000013	homing endonuclease	RM
Pfam	UHGV-0021653_98	PF01541	N/A	N/A	GIY-YIG catalytic domain	GIY-YIG
NCBIFam	UHGV-0021653_98	TIGR01453.1	N/A	N/A	group I intron endonuclease	N/A
structural_annotation	UHGV-0021653_98	PF19835,PF13518,PF07453,TIGR01453	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_100	phrog_314	66.0	6.1e-19	homing endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_100	UniRef90_A0A7X9BSH5	79.7	0.0000000000000839	GIY-YIG nuclease family protein	N/A
eggNOG-mapper	UHGV-0021653_100	1476973.JMMB01000007_gene2015	77.8	0.0000000000000611	GIY-YIG type nucleases (URI domain)	N/A
Pfam	UHGV-0021653_100	PF01541	N/A	N/A	GIY-YIG catalytic domain	GIY-YIG
NCBIFam	UHGV-0021653_100	TIGR01453.1	N/A	N/A	group I intron endonuclease	N/A
UniRef90	UHGV-0021653_103	UniRef90_A0A417JTJ0	75.9	2.07e-16	Polya polymerase	N/A
eggNOG-mapper	UHGV-0021653_103	1007096.BAGW01000018_gene677	62.0	0.000000000011	N/A	N/A
structural_annotation	UHGV-0021653_103	NF008146,COG1925	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_104	phrog_850	317.8	0	RNA-binding protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_104	UniRef90_A0A843FJC6	484.0	0	N/A	N/A
eggNOG-mapper	UHGV-0021653_104	1541960.KQ78_01972	320.0	0	oxidoreductase activity	N/A
Pfam	UHGV-0021653_104	PF11443	N/A	N/A	N/A	DUF2828
COG	UHGV-0021653_104	COG2304	N/A	N/A	Secreted protein containing bacterial Ig-like domain and vWFA domain	N/A
structural_annotation	UHGV-0021653_104	PF11443,MF_01340,COG2304	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_106	K07175	157.0	0	phoH2; PhoH-like ATPase	N/A
PHROG	UHGV-0021653_106	phrog_2765	237.4	0	PhoH-like phosphate starvation-inducible	other
UniRef90	UHGV-0021653_106	UniRef90_A0A1C5UCD2	413.0	0	PhoH-like protein	N/A
eggNOG-mapper	UHGV-0021653_106	1123252.ATZF01000010_gene420	281.0	0	PIN domain	N/A
Pfam	UHGV-0021653_106	PF13638	N/A	N/A	PIN domain	PIN_4
Pfam	UHGV-0021653_106	PF02562	N/A	N/A	PhoH-like protein	PhoH
COG	UHGV-0021653_106	COG1875	N/A	N/A	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	N/A
structural_annotation	UHGV-0021653_106	PF02562,PF13638,PF09142,MF_00265,NF007827,NF009148,COG1875	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_107	K08640	108.0	2e-34	E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]	N/A
PHROG	UHGV-0021653_107	phrog_20388	164.8	0	endolysin	lysis
UniRef90	UHGV-0021653_107	UniRef90_A0A345BPY8	153.0	6.59e-38	PGRP protein	N/A
eggNOG-mapper	UHGV-0021653_107	1203606.HMPREF1526_00253	165.0	8.47786e-43	N-acetylmuramoyl-L-alanine amidase	N/A
Pfam	UHGV-0021653_107	PF18013	N/A	N/A	Phage tail lysozyme	Phage_lysozyme2
Pfam	UHGV-0021653_107	PF08291	N/A	N/A	Peptidase M15	Peptidase_M15_3
Pfam	UHGV-0021653_107	PF01471	N/A	N/A	Putative peptidoglycan binding domain	PG_binding_1
Pfam	UHGV-0021653_107	PF08239	N/A	N/A	Bacterial SH3 domain	SH3_3
COG	UHGV-0021653_107	COG0860	N/A	N/A	N-acetylmuramoyl-L-alanine amidase	N/A
PHROG	UHGV-0021653_109	phrog_559	112.6	5e-33	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_109	UniRef90_Q4Z9H0	72.0	0.000000000000817	ORF097	N/A
eggNOG-mapper	UHGV-0021653_109	881953.E0YIZ1_9CAUD	79.3	0.00000000000000206	HNH endonuclease	N/A
AcrCatalog	UHGV-0021653_109	cluster_5564	59.7	0.000000000000265	NA	N/A
KOfam	UHGV-0021653_110	K02470	508.7	0	gyrB; DNA gyrase subunit B [EC:5.6.2.2]	N/A
PHROG	UHGV-0021653_110	phrog_543	417.0	0	DNA topoisomerase II large subunit	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_110	UniRef90_A0A3B9Z7X0	694.0	0	DNA topoisomerase (ATP-hydrolyzing)	N/A
eggNOG-mapper	UHGV-0021653_110	390874.Tpet_0094	322.0	0	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	N/A
Pfam	UHGV-0021653_110	PF00204	N/A	N/A	DNA gyrase B	DNA_gyraseB
Pfam	UHGV-0021653_110	PF01751	N/A	N/A	Toprim domain	Toprim
Pfam	UHGV-0021653_110	PF00986	N/A	N/A	DNA gyrase B subunit, carboxyl terminus	DNA_gyraseB_C
COG	UHGV-0021653_110	COG0187	N/A	N/A	DNA gyrase/topoisomerase IV, subunit B	N/A
structural_annotation	UHGV-0021653_110	PF00204,MF_01898,TIGR01059,COG0187	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_111	K02469	811.1	0	gyrA; DNA gyrase subunit A [EC:5.6.2.2]	N/A
PHROG	UHGV-0021653_111	phrog_551	429.2	0	DNA topoisomerase II	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_111	UniRef90_A0A3B9Z7C8	800.0	0	DNA topoisomerase (ATP-hydrolyzing)	N/A
eggNOG-mapper	UHGV-0021653_111	639282.DEFDS_0004	522.0	0	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	N/A
Pfam	UHGV-0021653_111	PF00521	N/A	N/A	DNA gyrase/topoisomerase IV, subunit A	DNA_topoisoIV
Pfam	UHGV-0021653_111	PF03989	N/A	N/A	DNA gyrase C-terminal domain, beta-propeller	DNA_gyraseA_C
COG	UHGV-0021653_111	COG0188	N/A	N/A	DNA gyrase/topoisomerase IV, subunit A	N/A
structural_annotation	UHGV-0021653_111	PF00521,PF03989,MF_01897,NF004043,COG0188	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_112	K01972	587.6	0	E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]	N/A
PHROG	UHGV-0021653_112	phrog_3869	548.5	0	NAD-dependent DNA ligase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_112	UniRef90_A0A843FQD5	665.0	0	DNA ligase	N/A
eggNOG-mapper	UHGV-0021653_112	411470.RUMGNA_00017	529.0	0	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	N/A
Pfam	UHGV-0021653_112	PF01653	N/A	N/A	NAD-dependent DNA ligase adenylation domain	DNA_ligase_aden
Pfam	UHGV-0021653_112	PF03120	N/A	N/A	NAD-dependent DNA ligase OB-fold domain	DNA_ligase_OB
Pfam	UHGV-0021653_112	PF12826	N/A	N/A	Helix-hairpin-helix motif	HHH_2
Pfam	UHGV-0021653_112	PF00533	N/A	N/A	BRCA1 C Terminus (BRCT) domain	BRCT
NCBIFam	UHGV-0021653_112	NF005932.1	N/A	N/A	NAD-dependent DNA ligase LigA	N/A
COG	UHGV-0021653_112	COG0272	N/A	N/A	NAD-dependent DNA ligase	N/A
HAMAP	UHGV-0021653_112	MF_01588	N/A	N/A	DNA ligase [ligA]	N/A
structural_annotation	UHGV-0021653_112	PF01653,PF03120,PF00533,MF_01588,NF005932,COG0272	N/A	N/A	N/A	N/A
UniRef90	UHGV-0021653_114	UniRef90_A0A843GM87	63.2	0.0000000000775	MarR family transcriptional regulator	N/A
structural_annotation	UHGV-0021653_114	PF04182,MF_01909,NF040939,COG1675	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_115	phrog_7168	48.8	0.00000000000011	homing endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_115	UniRef90_A0A843FP25	200.0	0	GIY-YIG nuclease family protein	N/A
eggNOG-mapper	UHGV-0021653_115	476272.RUMHYD_01972	62.4	0.0000000327	GIY-YIG type nucleases (URI domain)	N/A
Pfam	UHGV-0021653_115	PF01541	N/A	N/A	GIY-YIG catalytic domain	GIY-YIG
COG	UHGV-0021653_115	COG3860	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_115	PF19835,TIGR01453	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_117	K00560	162.3	0	thyA, TYMS; thymidylate synthase [EC:2.1.1.45]	N/A
PHROG	UHGV-0021653_117	phrog_5682	201.7	0	thymidylate synthase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_117	UniRef90_A0A415HVY4	372.0	0	Thymidylate synthase	N/A
eggNOG-mapper	UHGV-0021653_117	1410633.JHWR01000014_gene1762	335.0	0	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	N/A
Pfam	UHGV-0021653_117	PF00303	N/A	N/A	Thymidylate synthase	Thymidylat_synt
COG	UHGV-0021653_117	COG0207	N/A	N/A	Thymidylate synthase	N/A
HAMAP	UHGV-0021653_117	MF_00008	N/A	N/A	Thymidylate synthase [thyA]	N/A
structural_annotation	UHGV-0021653_117	PF00303,MF_00008,NF002497,COG0207	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_118	K00287	151.5	4.2039e-45	DHFR, folA; dihydrofolate reductase [EC:1.5.1.3]	N/A
PHROG	UHGV-0021653_118	phrog_316	132.7	1.8e-39	dihydrofolate reductase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_118	UniRef90_A0A374LFN6	144.0	6.23998e-41	Dihydrofolate reductase	N/A
eggNOG-mapper	UHGV-0021653_118	411460.RUMTOR_02358	132.0	2.35e-37	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	N/A
Pfam	UHGV-0021653_118	PF00186	N/A	N/A	Dihydrofolate reductase	DHFR_1
COG	UHGV-0021653_118	COG0262	N/A	N/A	Dihydrofolate reductase	N/A
structural_annotation	UHGV-0021653_118	PF00186,NF000143,COG0262	N/A	N/A	N/A	N/A
UniRef90	UHGV-0021653_119	UniRef90_A0A843FPF0	119.0	1.31e-32	Winged helix-turn-helix domain-containing protein	N/A
structural_annotation	UHGV-0021653_119	PF03444,MF_00732,TIGR02337,COG1321	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_120	phrog_2367	56.5	2.8e-16	N/A	unknown function
structural_annotation	UHGV-0021653_120	PF00436,PF19649,MF_00984,NF004476,COG2965	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_121	phrog_124	165.4	0	Sak4-like ssDNA annealing protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_121	UniRef90_A0A843GMB3	246.0	0	ATP-binding protein	N/A
eggNOG-mapper	UHGV-0021653_121	1541960.KQ78_01919	194.0	0	Belongs to the helicase family. UvrD subfamily	N/A
Pfam	UHGV-0021653_121	PF13479	N/A	N/A	AAA domain	AAA_24
COG	UHGV-0021653_121	COG2887	N/A	N/A	RecB family exonuclease	N/A
structural_annotation	UHGV-0021653_121	PF13479,MF_00350,TIGR01618,COG0468	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_122	phrog_4680	54.4	0.0000000000000022	N/A	unknown function
eggNOG-mapper	UHGV-0021653_122	1541960.KQ78_01918	73.6	0.00000000000000138	N/A	N/A
KOfam	UHGV-0021653_123	K02314	81.1	1.3e-23	dnaB; replicative DNA helicase [EC:5.6.2.3]	N/A
PHROG	UHGV-0021653_123	phrog_19	102.6	3.3e-30	DnaB-like replicative helicase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_123	UniRef90_A0A843FVR3	459.0	0	DNA helicase	N/A
eggNOG-mapper	UHGV-0021653_123	224308.BSU20370	244.0	0	DnaB-like helicase C terminal domain	N/A
Pfam	UHGV-0021653_123	PF00772	N/A	N/A	DnaB-like helicase N terminal domain	DnaB
Pfam	UHGV-0021653_123	PF03796	N/A	N/A	DnaB-like helicase C terminal domain	DnaB_C
COG	UHGV-0021653_123	COG0305	N/A	N/A	Replicative DNA helicase	N/A
structural_annotation	UHGV-0021653_123	PF03796,PF00772,MF_04155,TIGR00665,COG0305	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_124	phrog_7168	118.3	3.4e-37	homing endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_124	UniRef90_UPI0011A028AF	146.0	5.03999e-40	GIY-YIG nuclease family protein	N/A
eggNOG-mapper	UHGV-0021653_124	1126950.G9J202_9CAUD	75.9	0.000000000000064	nucleic acid binding	N/A
Pfam	UHGV-0021653_124	PF01541	N/A	N/A	GIY-YIG catalytic domain	GIY-YIG
NCBIFam	UHGV-0021653_124	TIGR01453.1	N/A	N/A	group I intron endonuclease	N/A
structural_annotation	UHGV-0021653_124	PF19835,PF02796,TIGR01453	N/A	N/A	N/A	N/A
UniRef90	UHGV-0021653_125	UniRef90_A0A345BPT8	85.9	3.72e-20	Replicative DNA helicase	N/A
eggNOG-mapper	UHGV-0021653_125	537007.BLAHAN_05495	57.8	0.0000000123	DnaB-like helicase C terminal domain	N/A
COG	UHGV-0021653_125	COG0305	N/A	N/A	Replicative DNA helicase	N/A
KOfam	UHGV-0021653_127	K02316	52.5	0.0000000000000056	dnaG; DNA primase [EC:2.7.7.101]	N/A
PHROG	UHGV-0021653_127	phrog_47	90.4	2.4e-26	DNA primase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_127	UniRef90_A0A356MLE3	297.0	0	Toprim domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_127	224308.BSU20360	215.0	0	DNA primase activity	N/A
COG	UHGV-0021653_127	COG0358	N/A	N/A	DNA primase (bacterial type)	N/A
structural_annotation	UHGV-0021653_127	PF01807,PF19898,MF_00974,NF006382,COG0358	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_128	phrog_4645	169.9	0	endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_128	UniRef90_A0A316L2P9	278.0	0	LAGLIDADG_2 domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_128	458639.A7KV45_9CAUD	119.0	8.84e-29	N-acetyltransferase activity	N/A
Pfam	UHGV-0021653_128	PF13412	N/A	N/A	Winged helix-turn-helix DNA-binding	HTH_24
structural_annotation	UHGV-0021653_128	PF05203,PF02796,PF19575,MF_01420,TIGR00647,NF040595,COG1481,COG3415	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_129	K07462	214.6	0	recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]	N/A
PHROG	UHGV-0021653_129	phrog_2484	353.5	0	RecJ-like ssDNA exonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_129	UniRef90_A0A843FU26	490.0	0	DHH family phosphoesterase	N/A
eggNOG-mapper	UHGV-0021653_129	665956.HMPREF1032_03163	301.0	0	exonuclease	N/A
Pfam	UHGV-0021653_129	PF01368	N/A	N/A	DHH family	DHH
Pfam	UHGV-0021653_129	PF17768	N/A	N/A	RecJ OB domain	RecJ_OB
COG	UHGV-0021653_129	COG0608	N/A	N/A	ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation	N/A
structural_annotation	UHGV-0021653_129	PF17768,PF02272,MF_00207,TIGR00644,COG0608	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_133	K03581	60.8	6.1e-18	recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]	N/A
PHROG	UHGV-0021653_133	phrog_325	130.0	1.7e-38	Dda-like helicase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_133	UniRef90_A0A843GQ82	243.0	0	AAA family ATPase	N/A
eggNOG-mapper	UHGV-0021653_133	1088721.NSU_0291	104.0	5.99e-23	UvrD-like helicase C-terminal domain	N/A
Pfam	UHGV-0021653_133	PF13538	N/A	N/A	UvrD-like helicase C-terminal domain	UvrD_C_2
COG	UHGV-0021653_133	COG0507	N/A	N/A	ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V)	N/A
structural_annotation	UHGV-0021653_133	MF_03176,TIGR01447	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_134	K02337	397.4	0	dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]	N/A
PHROG	UHGV-0021653_134	phrog_405	506.6	0	DNA polymerase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_134	UniRef90_A0A843FMN7	949.0	0	DNA-directed DNA polymerase	N/A
eggNOG-mapper	UHGV-0021653_134	224308.BSU20340	535.0	0	DNA polymerase	N/A
Pfam	UHGV-0021653_134	PF02811	N/A	N/A	PHP domain	PHP
Pfam	UHGV-0021653_134	PF07733	N/A	N/A	Bacterial DNA polymerase III alpha NTPase domain	DNA_pol3_alpha
Pfam	UHGV-0021653_134	PF17657	N/A	N/A	Bacterial DNA polymerase III alpha subunit finger domain	DNA_pol3_finger
COG	UHGV-0021653_134	COG0587	N/A	N/A	DNA polymerase III, alpha subunit	N/A
structural_annotation	UHGV-0021653_134	PF07733,PF02811,PF17657,MF_01902,NF005617,COG0587	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_135	phrog_7168	68.5	7.6e-24	homing endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_135	UniRef90_A0A7X9B987	95.9	5.56e-21	GIY-YIG nuclease family protein	N/A
KOfam	UHGV-0021653_136	K02337	136.2	2.10195e-43	dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]	N/A
PHROG	UHGV-0021653_136	phrog_20695	372.6	0	DNA binding protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_136	UniRef90_A0A1C3SDZ5	379.0	0	DNA-directed DNA polymerase	N/A
eggNOG-mapper	UHGV-0021653_136	1236976.JCM16418_4598	379.0	0	DNA polymerase	N/A
Pfam	UHGV-0021653_136	PF17657	N/A	N/A	Bacterial DNA polymerase III alpha subunit finger domain	DNA_pol3_finger
Pfam	UHGV-0021653_136	PF14579	N/A	N/A	Helix-hairpin-helix motif	HHH_6
COG	UHGV-0021653_136	COG0587	N/A	N/A	DNA polymerase III, alpha subunit	N/A
structural_annotation	UHGV-0021653_136	PF17657,PF14579,PF16100,MF_01902,NF005617,COG0587	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_137	K00942	51.3	0.000000000000011	gmk, GUK1; guanylate kinase [EC:2.7.4.8]	N/A
PHROG	UHGV-0021653_137	phrog_1815	105.1	6.4e-31	guanylate kinase	other
UniRef90	UHGV-0021653_137	UniRef90_A0A133N9K8	78.6	0.0000000000000415	Guanylate kinase	N/A
eggNOG-mapper	UHGV-0021653_137	195103.CPF_2762	78.6	0.00000000000000695	Guanylate kinase	N/A
Pfam	UHGV-0021653_137	PF00625	N/A	N/A	Guanylate kinase	Guanylate_kin
COG	UHGV-0021653_137	COG0194	N/A	N/A	Guanylate kinase	N/A
KOfam	UHGV-0021653_138	K21636	431.8	0	nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]	N/A
PHROG	UHGV-0021653_138	phrog_487	589.6	0	NrdD-like anaerobic ribonucleotide reductase large subunit	moron, auxiliary metabolic gene and host takeover
UniRef90	UHGV-0021653_138	UniRef90_R7F5N5	947.0	0	Anaerobic ribonucleoside-triphosphate reductase	N/A
eggNOG-mapper	UHGV-0021653_138	500635.MITSMUL_03099	824.0	0	Ribonucleoside-triphosphate reductase	N/A
Pfam	UHGV-0021653_138	PF03477	N/A	N/A	ATP cone domain	ATP-cone
Pfam	UHGV-0021653_138	PF13597	N/A	N/A	Anaerobic ribonucleoside-triphosphate reductase	NRDD
NCBIFam	UHGV-0021653_138	NF006732.0	N/A	N/A	anaerobic ribonucleoside-triphosphate reductase	N/A
COG	UHGV-0021653_138	COG1328	N/A	N/A	Anaerobic ribonucleoside-triphosphate reductase	N/A
structural_annotation	UHGV-0021653_138	PF13597,PF03477,MF_00440,MF_02058,NF006732,COG1328	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_139	phrog_559	43.1	0.0000000000067	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_139	UniRef90_A0A4R6BQ44	53.1	0.000000385	N/A	N/A
eggNOG-mapper	UHGV-0021653_139	35241.Q9AYW5_BPTU2	52.0	0.00000159	N/A	N/A
KOfam	UHGV-0021653_140	K04068	135.1	4.9e-40	nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4]	N/A
PHROG	UHGV-0021653_140	phrog_626	121.9	2.9e-36	anaerobic ribonucleotide reductase small subunit	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_140	UniRef90_A0A843FG79	166.0	0	Anaerobic ribonucleoside-triphosphate reductase activating protein	N/A
eggNOG-mapper	UHGV-0021653_140	1499683.CCFF01000016_gene804	126.0	5.92e-35	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	N/A
Pfam	UHGV-0021653_140	PF13353	N/A	N/A	4Fe-4S single cluster domain	Fer4_12
COG	UHGV-0021653_140	COG0602	N/A	N/A	Organic radical activating enzyme NrdG/QueE	N/A
structural_annotation	UHGV-0021653_142	PF04937,MF_00034,NF001026,COG0816	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_143	PF10750,MF_01122,NF003088,COG1581	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_144	K01520	72.4	6.6e-21	dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]	N/A
PHROG	UHGV-0021653_144	phrog_135	77.2	2e-22	dUTPase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_144	UniRef90_A0A843FIU7	164.0	0	dUTPase domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_144	1158610.UC3_00179	125.0	2.7e-34	dUTPase	N/A
Pfam	UHGV-0021653_144	PF00692	N/A	N/A	dUTPase	dUTPase
COG	UHGV-0021653_144	COG0756	N/A	N/A	dUTP pyrophosphatase (dUTPase)	N/A
structural_annotation	UHGV-0021653_144	PF00692,MF_00116,NF010561,COG0756	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_145	K01159	56.1	5.1e-16	ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]	N/A
PHROG	UHGV-0021653_145	phrog_159	64.8	1.1e-18	RuvC-like Holliday junction resolvase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_145	UniRef90_A0A7X8D1J2	102.0	9.91e-25	Crossover junction endodeoxyribonuclease RuvC	N/A
eggNOG-mapper	UHGV-0021653_145	871968.DESME_08990	98.2	9.18e-24	N/A	N/A
Pfam	UHGV-0021653_145	PF02075	N/A	N/A	Crossover junction endodeoxyribonuclease RuvC	RuvC
structural_annotation	UHGV-0021653_145	PF07066,MF_00034,NF000711,COG0817	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_146	phrog_4105	49.5	0.000000000000033	N/A	unknown function
PHROG	UHGV-0021653_147	phrog_1233	61.2	1.7e-17	N/A	unknown function
structural_annotation	UHGV-0021653_147	PF13058	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0021653_148	658655.HMPREF0988_00915	55.8	0.000000272	N/A	N/A
PHROG	UHGV-0021653_149	phrog_20016	194.3	0	N/A	unknown function
UniRef90	UHGV-0021653_149	UniRef90_A0A345BPX4	164.0	0	Carbohydrate binding domain/collagen triple helix repeat protein	N/A
eggNOG-mapper	UHGV-0021653_149	397290.C810_05214	164.0	0	N/A	N/A
structural_annotation	UHGV-0021653_149	PF18573,NF033147	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_150	phrog_16490	132.2	2.5e-40	N/A	unknown function
eggNOG-mapper	UHGV-0021653_150	1408437.JNJN01000043_gene803	163.0	0	N/A	N/A
eggNOG-mapper	UHGV-0021653_151	476272.RUMHYD_01953	68.6	0.0000000000000249	N/A	N/A
PHROG	UHGV-0021653_153	phrog_13712	122.1	4e-36	holin	lysis
eggNOG-mapper	UHGV-0021653_153	1235800.C819_00457	83.6	9.89e-19	N/A	N/A
eggNOG-mapper	UHGV-0021653_154	1304866.K413DRAFT_4770	86.7	5.3e-17	PFAM Formylglycine-generating sulfatase enzyme	N/A
COG	UHGV-0021653_154	COG1262	N/A	N/A	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	N/A
structural_annotation	UHGV-0021653_154	PF10651	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0021653_155	742733.HMPREF9469_00973	80.9	0.000000000000665	N/A	N/A
structural_annotation	UHGV-0021653_155	PF10651,NF010681	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_157	phrog_14959	71.2	0	N/A	unknown function
eggNOG-mapper	UHGV-0021653_157	1127696.HMPREF9134_00818	64.3	0.000000762	N/A	N/A
structural_annotation	UHGV-0021653_158	MF_01186	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0021653_159	411470.RUMGNA_02068	79.0	0.0000000000000682	N/A	N/A
PHROG	UHGV-0021653_160	phrog_35541	108.0	2.4e-34	N/A	unknown function
UniRef90	UHGV-0021653_160	UniRef90_A0A3D6B2G4	170.0	3.08286e-44	Mtd_N domain-containing protein	N/A
PHROG	UHGV-0021653_163	phrog_32343	115.6	1.4013e-45	N/A	unknown function
UniRef90	UHGV-0021653_163	UniRef90_A0A345BPW9	199.0	0	Putative flagellin-like protein	N/A
structural_annotation	UHGV-0021653_163	PF05113,NF033848,COG4379	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_164	PF21821,PF12245,PF16974,PF17166,MF_04116,TIGR01633,TIGR03503,COG4228,COG4885	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_168	K20478	108.3	7e-33	GOLGB1; golgin subfamily B member 1	N/A
PHROG	UHGV-0021653_168	phrog_4211	152.1	0	tail length tape measure protein	tail
eggNOG-mapper	UHGV-0021653_168	1274524.BSONL12_21499	73.9	0.000000000958	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	N/A
Pfam	UHGV-0021653_168	PF10145	N/A	N/A	Phage-related minor tail protein	PhageMin_Tail
NCBIFam	UHGV-0021653_168	TIGR01760.1	N/A	N/A	phage tail tape measure protein	N/A
COG	UHGV-0021653_168	COG0739	N/A	N/A	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain	N/A
PHROG	UHGV-0021653_169	phrog_30570	58.2	1.1e-16	N/A	unknown function
PHROG	UHGV-0021653_172	phrog_2729	118.1	3e-35	virion structural protein	head and packaging
PHROG	UHGV-0021653_173	phrog_59	93.2	0	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_173	UniRef90_A0A6G6XQG0	105.0	1.45e-22	Endonuclease	N/A
eggNOG-mapper	UHGV-0021653_173	212035.YL245_MIMIV	95.5	7.12e-20	HNH endonuclease	N/A
PADLOC	UHGV-0021653_173	HEase_00016	61.2	1.6e-31	homing endonuclease	RM
Pfam	UHGV-0021653_173	PF07463	N/A	N/A	NUMOD4 motif	NUMOD4
Pfam	UHGV-0021653_173	PF13392	N/A	N/A	HNH endonuclease	HNH_3
PHROG	UHGV-0021653_174	phrog_2729	52.6	0.0000000000000057	virion structural protein	head and packaging
eggNOG-mapper	UHGV-0021653_174	1560313.A0A0D3MTD7_9CAUD	59.7	0.000000000747	N/A	N/A
PHROG	UHGV-0021653_175	phrog_4051	93.8	1.8e-27	N/A	unknown function
PHROG	UHGV-0021653_176	phrog_6123	67.7	7.5e-20	virion structural protein	head and packaging
structural_annotation	UHGV-0021653_176	PF06141	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_177	phrog_31155	70.1	3.1e-20	N/A	unknown function
structural_annotation	UHGV-0021653_177	PF19408,PF11649,NF041894,COG5614	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_178	phrog_29637	61.6	1e-17	N/A	unknown function
structural_annotation	UHGV-0021653_178	PF14276,COG1516	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_179	phrog_3853	120.9	5e-36	N/A	unknown function
PHROG	UHGV-0021653_181	phrog_4088	204.7	0	N/A	unknown function
eggNOG-mapper	UHGV-0021653_181	1541960.KQ78_01850	172.0	0	N/A	N/A
structural_annotation	UHGV-0021653_181	PF05065,MF_04119,TIGR01554,COG4653	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_183	phrog_3313	133.1	2.9e-40	N/A	unknown function
UniRef90	UHGV-0021653_183	UniRef90_A0A843FJ52	152.0	2.05e-38	HALZ domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_183	1308863.U5J9D4_9CAUD	103.0	5.86e-21	N/A	N/A
structural_annotation	UHGV-0021653_183	PF04586,TIGR01543,COG3566	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_184	phrog_2739	257.8	0	portal protein	head and packaging
UniRef90	UHGV-0021653_184	UniRef90_A0A345BPV2	440.0	0	Putative portal protein	N/A
eggNOG-mapper	UHGV-0021653_184	881953.E0YJ33_9CAUD	102.0	3.31e-20	N/A	N/A
structural_annotation	UHGV-0021653_184	PF05133,MF_04135,TIGR01537,COG4695	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_185	phrog_9084	91.2	1.3e-26	homing endonuclease	DNA, RNA and nucleotide metabolism
eggNOG-mapper	UHGV-0021653_185	632112.C1KFK2_9CAUD	52.4	0.0000032	regulation of transcription, DNA-dependent	N/A
structural_annotation	UHGV-0021653_185	PF18741,MF_04160,NF007294,COG2852	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_186	phrog_24618	158.8	0	N/A	unknown function
eggNOG-mapper	UHGV-0021653_186	1235802.C823_04558	72.4	0.00000000000477	N/A	N/A
PHROG	UHGV-0021653_187	phrog_59	124.8	4.4e-37	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_187	UniRef90_A0A481YQJ4	107.0	1.97e-23	HNH endonuclease	N/A
eggNOG-mapper	UHGV-0021653_187	212035.YL245_MIMIV	85.5	1.39e-16	HNH endonuclease	N/A
PADLOC	UHGV-0021653_187	HEase_00016	58.2	3.5e-24	homing endonuclease	RM
Pfam	UHGV-0021653_187	PF13392	N/A	N/A	HNH endonuclease	HNH_3
Pfam	UHGV-0021653_187	PF07453	N/A	N/A	NUMOD1 domain	NUMOD1
structural_annotation	UHGV-0021653_187	PF07453	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_188	phrog_7168	85.8	6.1e-25	homing endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_188	UniRef90_UPI00093DD291	211.0	0	GIY-YIG nuclease family protein	N/A
eggNOG-mapper	UHGV-0021653_188	476272.RUMHYD_01972	60.1	0.000000103	GIY-YIG type nucleases (URI domain)	N/A
PADLOC	UHGV-0021653_188	HEase_00030	53.2	0.0000000000000049	homing endonuclease	RM
Pfam	UHGV-0021653_188	PF01541	N/A	N/A	GIY-YIG catalytic domain	GIY-YIG
COG	UHGV-0021653_188	COG3860	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_188	PF01541,PF02796,TIGR01453	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_189	phrog_15503	118.7	4.1e-35	N/A	unknown function
UniRef90	UHGV-0021653_189	UniRef90_A0A7T3K9G8	58.5	0.000000238	Helicase_RecD domain-containing protein	N/A
eggNOG-mapper	UHGV-0021653_189	1235793.C809_01156	67.8	0.0000000000793	N/A	N/A
PHROG	UHGV-0021653_191	phrog_3314	72.1	5.7e-21	N/A	unknown function
PHROG	UHGV-0021653_192	phrog_3314	152.4	2.8026e-45	N/A	unknown function
PHROG	UHGV-0021653_193	phrog_5767	124.4	1.8e-39	sigma factor	transcription regulation
UniRef90	UHGV-0021653_193	UniRef90_A0A345BPU6	327.0	0	HTH DNA binding domain protein	N/A
eggNOG-mapper	UHGV-0021653_193	1123239.KB898628_gene3218	72.0	0.0000000000724	N/A	N/A
COG	UHGV-0021653_195	COG2002	N/A	N/A	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	N/A
PHROG	UHGV-0021653_210	phrog_2131	87.5	1e-25	N/A	unknown function
eggNOG-mapper	UHGV-0021653_210	1445810.A0A0A0PKY2_9CAUD	103.0	1.96e-26	N/A	N/A
structural_annotation	UHGV-0021653_222	PF11019,MF_01022,NF003937,COG4502	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0021653_223	469596.HMPREF9488_03215	68.2	0.000000000000834	N/A	N/A
structural_annotation	UHGV-0021653_223	PF16475	N/A	N/A	N/A	N/A
KOfam	UHGV-0021653_224	K08728	62.5	5.6e-18	E2.4.2.6; nucleoside deoxyribosyltransferase [EC:2.4.2.6]	N/A
PHROG	UHGV-0021653_224	phrog_7995	86.1	4.1e-25	nucleoside deoxyribosyltransferase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0021653_224	UniRef90_R6N3L6	122.0	2.86e-33	Nucleoside 2-deoxyribosyltransferase	N/A
eggNOG-mapper	UHGV-0021653_224	633697.EubceDRAFT1_0395	99.0	1.33e-24	Nucleoside 2-deoxyribosyltransferase	N/A
Pfam	UHGV-0021653_224	PF05014	N/A	N/A	Nucleoside 2-deoxyribosyltransferase	Nuc_deoxyrib_tr
COG	UHGV-0021653_224	COG3613	N/A	N/A	Nucleoside 2-deoxyribosyltransferase	N/A
structural_annotation	UHGV-0021653_224	PF05014,MF_03036,TIGR03646,COG3613	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_232	PF00679,MF_01515,NF003194,COG4843	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_234	PF07106,MF_01177,NF000244,COG3682	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_236	phrog_20187	64.0	2.1e-35	N/A	unknown function
UniRef90	UHGV-0021653_236	UniRef90_A0A345BPQ2	236.0	0	Putative Pol III-like exoribonuclease	N/A
structural_annotation	UHGV-0021653_236	PF13361,NF006316,COG0847	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0021653_243	PF18903	N/A	N/A	N/A	N/A
PHROG	UHGV-0021653_244	phrog_559	56.6	3.9e-16	HNH endonuclease	DNA, RNA and nucleotide metabolism
eggNOG-mapper	UHGV-0021653_244	886882.PPSC2_p0627	63.5	0.00000000473	Restriction endonuclease	N/A
Pfam	UHGV-0021653_244	PF10881	N/A	N/A	N/A	DUF2726
COG	UHGV-0021653_244	COG3440	N/A	N/A	Predicted restriction endonuclease	N/A
structural_annotation	UHGV-0021653_245	PF04182,NF038290	N/A	N/A	N/A	N/A
Pfam	UHGV-0021653_246	PF01541	N/A	N/A	GIY-YIG catalytic domain	GIY-YIG