eggNOG-mapper | UHGV-0227382_1 | 411461.DORFOR_00905 | 101.0 | 1.71e-24 | Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone | N/A |
COG | UHGV-0227382_1 | COG0550 | N/A | N/A | DNA topoisomerase IA | N/A |
PHROG | UHGV-0227382_2 | phrog_9243 | 62.1 | 7.9e-18 | N/A | unknown function |
UniRef90 | UHGV-0227382_2 | UniRef90_UPI001CEC222A | 217.0 | 0 | N/A | N/A |
eggNOG-mapper | UHGV-0227382_2 | 1118057.CAGX01000067_gene1128 | 224.0 | 0 | N/A | N/A |
Pfam | UHGV-0227382_2 | PF12686 | N/A | N/A | N/A | DUF3800 |
structural_annotation | UHGV-0227382_2 | MF_00052_A,NF011119 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_3 | phrog_13890 | 47.5 | 0.00000000000022 | N/A | unknown function |
structural_annotation | UHGV-0227382_6 | NF041070 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_8 | phrog_1535 | 84.8 | 1.3e-38 | tail length tape measure protein | tail |
UniRef90 | UHGV-0227382_8 | UniRef90_A0A810PX76 | 124.0 | 6.04e-26 | Phage tail tape measure protein | N/A |
eggNOG-mapper | UHGV-0227382_8 | 693746.OBV_18190 | 134.0 | 1.12e-29 | domain protein | N/A |
COG | UHGV-0227382_8 | COG1511 | N/A | N/A | N/A | N/A |
structural_annotation | UHGV-0227382_8 | PF05546,TIGR02559 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_9 | phrog_706 | 121.8 | 4.6e-36 | N/A | unknown function |
UniRef90 | UHGV-0227382_9 | UniRef90_UPI001D069FB9 | 210.0 | 0 | Gp15 family bacteriophage protein | N/A |
eggNOG-mapper | UHGV-0227382_9 | 693746.OBV_18170 | 196.0 | 0 | Bacteriophage Gp15 protein | N/A |
Pfam | UHGV-0227382_9 | PF06854 | N/A | N/A | Bacteriophage Gp15 protein | Phage_Gp15 |
structural_annotation | UHGV-0227382_9 | PF06854 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_10 | phrog_11299 | 75.0 | 1.1e-21 | N/A | unknown function |
eggNOG-mapper | UHGV-0227382_10 | 693746.OBV_18160 | 169.0 | 0 | N/A | N/A |
structural_annotation | UHGV-0227382_10 | PF10666 | N/A | N/A | N/A | N/A |
eggNOG-mapper | UHGV-0227382_14 | 1009370.ALO_17461 | 69.7 | 0.000000000000129 | N/A | N/A |
KOfam | UHGV-0227382_15 | K03091 | 46.3 | 0.00000000000077 | sigH; RNA polymerase sporulation-specific sigma factor | N/A |
PHROG | UHGV-0227382_15 | phrog_351 | 44.4 | 0.0000000000000041 | RNA polymerase sigma factor | transcription regulation |
UniRef90 | UHGV-0227382_15 | UniRef90_UPI001F4290AF | 148.0 | 1.73999e-41 | sigma-70 family RNA polymerase sigma factor | N/A |
eggNOG-mapper | UHGV-0227382_15 | 720554.Clocl_0693 | 54.3 | 0.00000359 | Sigma-70, region 4 | N/A |
COG | UHGV-0227382_15 | COG0568 | N/A | N/A | DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) | N/A |
structural_annotation | UHGV-0227382_15 | PF07638,MF_00959,NF006147,COG0568 | N/A | N/A | N/A | N/A |
KOfam | UHGV-0227382_16 | K02315 | 158.5 | 0 | dnaC; DNA replication protein DnaC | N/A |
PHROG | UHGV-0227382_16 | phrog_50 | 150.0 | 1.54143e-44 | DnaC-like helicase loader | DNA, RNA and nucleotide metabolism |
UniRef90 | UHGV-0227382_16 | UniRef90_UPI00195C3322 | 269.0 | 0 | ATP-binding protein | N/A |
eggNOG-mapper | UHGV-0227382_16 | 1121344.JHZO01000004_gene1170 | 270.0 | 0 | N/A | N/A |
Pfam | UHGV-0227382_16 | PF01695 | N/A | N/A | IstB-like ATP binding protein | IstB_IS21 |
NCBIFam | UHGV-0227382_16 | NF005992.0 | N/A | N/A | hypothetical protein | N/A |
COG | UHGV-0227382_16 | COG1484 | N/A | N/A | DNA replication protein DnaC | N/A |
structural_annotation | UHGV-0227382_16 | PF01695,MF_01158,NF005992,COG1484 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_17 | phrog_5708 | 154.9 | 0 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
UniRef90 | UHGV-0227382_17 | UniRef90_A0A2K4QBX8 | 146.0 | 5.55e-40 | Phg_2220_C domain-containing protein | N/A |
eggNOG-mapper | UHGV-0227382_17 | 1203606.HMPREF1526_00313 | 147.0 | 3.78995e-41 | DnaD domain protein | N/A |
COG | UHGV-0227382_17 | COG3935 | N/A | N/A | DNA replication protein DnaD | N/A |
structural_annotation | UHGV-0227382_17 | PF09681,TIGR01714 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_18 | phrog_2113 | 45.5 | 0.00000000000091 | N/A | unknown function |
eggNOG-mapper | UHGV-0227382_18 | 1160721.RBI_II00485 | 55.1 | 0.000000019 | N/A | N/A |
structural_annotation | UHGV-0227382_18 | PF08279,COG1654 | N/A | N/A | N/A | N/A |
UniRef90 | UHGV-0227382_19 | UniRef90_UPI000994F32A | 47.8 | 0.00000874 | helix-turn-helix domain-containing protein | N/A |
Pfam | UHGV-0227382_19 | PF12728 | N/A | N/A | Helix-turn-helix domain | HTH_17 |
NCBIFam | UHGV-0227382_19 | TIGR01764.1 | N/A | N/A | excisionase family DNA-binding protein | N/A |
structural_annotation | UHGV-0227382_19 | PF12728,TIGR01764,COG3311 | N/A | N/A | N/A | N/A |
eggNOG-mapper | UHGV-0227382_20 | 552398.HMPREF0866_02243 | 88.6 | 1.04e-21 | Helix-turn-helix XRE-family like proteins | N/A |
PHROG | UHGV-0227382_21 | phrog_4292 | 83.1 | 1.8e-24 | N/A | unknown function |
UniRef90 | UHGV-0227382_21 | UniRef90_I7J4K2 | 56.6 | 0.00000000149 | Phage related protein | N/A |
eggNOG-mapper | UHGV-0227382_21 | 552398.HMPREF0866_02241 | 97.1 | 2.53e-26 | N/A | N/A |
eggNOG-mapper | UHGV-0227382_22 | 552398.HMPREF0866_02239 | 582.0 | 0 | N/A | N/A |
structural_annotation | UHGV-0227382_22 | PF01649,MF_00500,TIGR00029,COG0268 | N/A | N/A | N/A | N/A |
UniRef90 | UHGV-0227382_23 | UniRef90_R5HBV6 | 248.0 | 0 | Translation initiation factor IF-2 | N/A |
eggNOG-mapper | UHGV-0227382_23 | 552398.HMPREF0866_02238 | 207.0 | 0 | N/A | N/A |
PHROG | UHGV-0227382_24 | phrog_1468 | 52.9 | 0.0000000000000036 | transcriptional repressor | transcription regulation |
UniRef90 | UHGV-0227382_24 | UniRef90_R5HCD6 | 144.0 | 9.24857e-44 | HTH cro/C1-type domain-containing protein | N/A |
eggNOG-mapper | UHGV-0227382_24 | 1297617.JPJD01000049_gene1336 | 137.0 | 1.24001e-41 | N/A | N/A |
Pfam | UHGV-0227382_24 | PF01381 | N/A | N/A | Helix-turn-helix | HTH_3 |
structural_annotation | UHGV-0227382_24 | PF01381,NF010465,COG3655 | N/A | N/A | N/A | N/A |
KOfam | UHGV-0227382_25 | K07497 | 66.6 | 4.6e-19 | K07497; putative transposase | N/A |
PHROG | UHGV-0227382_25 | phrog_310 | 351.0 | 0 | transposase | integration and excision |
UniRef90 | UHGV-0227382_25 | UniRef90_R5HRR1 | 1365.0 | 0 | Mu transposase C-superfamily | N/A |
eggNOG-mapper | UHGV-0227382_25 | 552398.HMPREF0866_02236 | 1293.0 | 0 | Mu transposase, C-terminal | N/A |
Pfam | UHGV-0227382_25 | PF02914 | N/A | N/A | Bacteriophage Mu transposase | DDE_2 |
Pfam | UHGV-0227382_25 | PF09299 | N/A | N/A | Mu transposase, C-terminal | Mu-transpos_C |
COG | UHGV-0227382_25 | COG2801 | N/A | N/A | Transposase InsO and inactivated derivatives | N/A |
structural_annotation | UHGV-0227382_25 | PF02914,PF09299,NF033594,COG2801 | N/A | N/A | N/A | N/A |
KOfam | UHGV-0227382_26 | K12283 | 41.1 | 0.000000000018 | mshM; MSHA biogenesis protein MshM | N/A |
PHROG | UHGV-0227382_26 | phrog_296 | 145.0 | 6.19374e-43 | DNA transposition protein | integration and excision |
UniRef90 | UHGV-0227382_26 | UniRef90_F4XF61 | 593.0 | 0 | AAA domain-containing protein | N/A |
eggNOG-mapper | UHGV-0227382_26 | 1297617.JPJD01000049_gene1334 | 596.0 | 0 | AAA domain | N/A |
Pfam | UHGV-0227382_26 | PF13401 | N/A | N/A | AAA domain | AAA_22 |
COG | UHGV-0227382_26 | COG2842 | N/A | N/A | Bacteriophage DNA transposition protein, AAA+ family ATPase | N/A |
structural_annotation | UHGV-0227382_26 | PF13401,MF_01407,TIGR03015,COG2842 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_27 | phrog_491 | 121.4 | 6e-36 | Mu Gam-like end protection | DNA, RNA and nucleotide metabolism |
UniRef90 | UHGV-0227382_27 | UniRef90_UPI00067F63B8 | 259.0 | 0 | host-nuclease inhibitor Gam family protein | N/A |
eggNOG-mapper | UHGV-0227382_27 | 552398.HMPREF0866_02234 | 310.0 | 0 | Bacteriophage Mu Gam like protein | N/A |
Pfam | UHGV-0227382_27 | PF07352 | N/A | N/A | Bacteriophage Mu Gam like protein | Phage_Mu_Gam |
COG | UHGV-0227382_27 | COG4396 | N/A | N/A | Mu-like prophage host-nuclease inhibitor protein Gam | N/A |
structural_annotation | UHGV-0227382_27 | PF07352,COG4396 | N/A | N/A | N/A | N/A |
KOfam | UHGV-0227382_28 | K05925 | 78.7 | 8.2e-23 | METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348] | N/A |
PHROG | UHGV-0227382_28 | phrog_359 | 218.7 | 0 | DNA methyltransferase | other |
UniRef90 | UHGV-0227382_28 | UniRef90_F4XF59 | 302.0 | 0 | Adenine-specific DNA methyltransferase (Fragment) | N/A |
eggNOG-mapper | UHGV-0227382_28 | 552398.HMPREF0866_02233 | 302.0 | 0 | Belongs to the MT-A70-like family | N/A |
PADLOC | UHGV-0227382_28 | MTase_II_00048 | 197.0 | 0 | Type II methyltransferase | RM |
Pfam | UHGV-0227382_28 | PF05063 | N/A | N/A | MT-A70 | MT-A70 |
COG | UHGV-0227382_28 | COG4725 | N/A | N/A | N6-adenosine-specific RNA methylase IME4 | N/A |
structural_annotation | UHGV-0227382_28 | PF05063,MF_01872,NF010253,COG4725 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_29 | phrog_286 | 94.0 | 1.6e-27 | N/A | unknown function |
UniRef90 | UHGV-0227382_29 | UniRef90_A0A2V2D3Z2 | 199.0 | 0 | Regulatory protein GemA | N/A |
eggNOG-mapper | UHGV-0227382_29 | 1297617.JPJD01000049_gene1331 | 255.0 | 0 | N/A | N/A |
Pfam | UHGV-0227382_29 | PF06252 | N/A | N/A | Bacteriophage Mu, GemA protein | GemA |
COG | UHGV-0227382_29 | COG4382 | N/A | N/A | N/A | N/A |
structural_annotation | UHGV-0227382_29 | PF06252,COG4382 | N/A | N/A | N/A | N/A |
UniRef90 | UHGV-0227382_30 | UniRef90_A0A416RDK2 | 224.0 | 0 | Translation initiation factor IF-2 | N/A |
eggNOG-mapper | UHGV-0227382_30 | 411483.FAEPRAA2165_03395 | 111.0 | 4.89e-30 | N/A | N/A |
PHROG | UHGV-0227382_32 | phrog_33075 | 137.3 | 4.69996e-41 | N/A | unknown function |
UniRef90 | UHGV-0227382_32 | UniRef90_A0A416REG9 | 246.0 | 0 | Addiction module toxin RelE | N/A |
eggNOG-mapper | UHGV-0227382_32 | 552398.HMPREF0866_02228 | 171.0 | 0 | SPTR Toxin-antitoxin system, toxin component, RelE family | N/A |
KOfam | UHGV-0227382_34 | K01448 | 87.3 | 1.8e-25 | amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | N/A |
PHROG | UHGV-0227382_34 | phrog_435 | 145.3 | 4.40008e-43 | endolysin | lysis |
UniRef90 | UHGV-0227382_34 | UniRef90_A0A1C6I5H7 | 805.0 | 0 | N-acetylmuramoyl-L-alanine amidase CwlD | N/A |
eggNOG-mapper | UHGV-0227382_34 | 1297617.JPJD01000049_gene1326 | 769.0 | 0 | N-acetylmuramoyl-L-alanine amidase | N/A |
Pfam | UHGV-0227382_34 | PF01520 | N/A | N/A | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
Pfam | UHGV-0227382_34 | PF01832 | N/A | N/A | Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase | Glucosaminidase |
COG | UHGV-0227382_34 | COG0860 | N/A | N/A | N-acetylmuramoyl-L-alanine amidase | N/A |
structural_annotation | UHGV-0227382_34 | PF01520,PF01832,MF_00562,TIGR02883,NF009355,COG0860,COG1705 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_35 | phrog_836 | 66.2 | 4.6e-19 | late transcriptional activator | transcription regulation |
UniRef90 | UHGV-0227382_35 | UniRef90_R5HBU0 | 242.0 | 0 | DNA-binding protein RdgB | N/A |
eggNOG-mapper | UHGV-0227382_35 | 1297617.JPJD01000049_gene1325 | 192.0 | 0 | Mor transcription activator family | N/A |
Pfam | UHGV-0227382_35 | PF08765 | N/A | N/A | Mor transcription activator family | Mor |
COG | UHGV-0227382_35 | COG5566 | N/A | N/A | Transcriptional regulator, middle operon regulator (Mor) family | N/A |
structural_annotation | UHGV-0227382_35 | PF08765,NF040785,COG5566 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_36 | phrog_36209 | 226.3 | 0 | holin | lysis |
UniRef90 | UHGV-0227382_36 | UniRef90_R5HGE4 | 312.0 | 0 | Collagen alpha-1(I) chain (Alpha-1 type I collagen) | N/A |
eggNOG-mapper | UHGV-0227382_36 | 1297617.JPJD01000049_gene1324 | 270.0 | 0 | N/A | N/A |
PHROG | UHGV-0227382_37 | phrog_462 | 44.2 | 0.0000000000026 | lipoprotein | other |
eggNOG-mapper | UHGV-0227382_37 | 552398.HMPREF0866_02224 | 164.0 | 0 | N/A | N/A |
PHROG | UHGV-0227382_38 | phrog_436 | 41.6 | 0.000000000013 | N/A | unknown function |
eggNOG-mapper | UHGV-0227382_38 | 1297617.JPJD01000049_gene1322 | 209.0 | 0 | N/A | N/A |
structural_annotation | UHGV-0227382_38 | PF10007,MF_01819,TIGR02337,COG1846 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_39 | phrog_426 | 108.1 | 9e-32 | terminase small subunit | head and packaging |
UniRef90 | UHGV-0227382_39 | UniRef90_UPI001AB02D0D | 279.0 | 0 | N/A | N/A |
eggNOG-mapper | UHGV-0227382_39 | 1297617.JPJD01000049_gene1321 | 337.0 | 0 | N/A | N/A |
Pfam | UHGV-0227382_39 | PF11985 | N/A | N/A | Bacteriophage Mu, Gp27 | Phage_Mu_Gp27 |
structural_annotation | UHGV-0227382_39 | PF11985 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_40 | phrog_38 | 275.3 | 0 | terminase large subunit | head and packaging |
UniRef90 | UHGV-0227382_40 | UniRef90_A0A6I2RII2 | 1118.0 | 0 | Phage terminase large subunit | N/A |
eggNOG-mapper | UHGV-0227382_40 | 1297617.JPJD01000049_gene1320 | 1155.0 | 0 | TIGRFAM Phage | N/A |
NCBIFam | UHGV-0227382_40 | TIGR01630.1 | N/A | N/A | phage terminase large subunit | N/A |
COG | UHGV-0227382_40 | COG5362 | N/A | N/A | Phage terminase large subunit | N/A |
structural_annotation | UHGV-0227382_40 | PF17289,PF03354,MF_04147,NF033889,COG5410,COG5362 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_41 | phrog_113 | 351.2 | 0 | portal protein | head and packaging |
UniRef90 | UHGV-0227382_41 | UniRef90_D7GRF1 | 816.0 | 0 | Mu-like prophage protein gp29 | N/A |
eggNOG-mapper | UHGV-0227382_41 | 1297617.JPJD01000049_gene1319 | 985.0 | 0 | N/A | N/A |
Pfam | UHGV-0227382_41 | PF06074 | N/A | N/A | N/A | DUF935 |
COG | UHGV-0227382_41 | COG4383 | N/A | N/A | N/A | N/A |
structural_annotation | UHGV-0227382_41 | PF06074,MF_04135,TIGR01538,COG4383 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_42 | phrog_220 | 180.9 | 0 | head morphogenesis | head and packaging |
UniRef90 | UHGV-0227382_42 | UniRef90_UPI00051C375A | 476.0 | 0 | minor capsid protein | N/A |
eggNOG-mapper | UHGV-0227382_42 | 1297617.JPJD01000049_gene1318 | 476.0 | 0 | Phage Mu protein F like protein | N/A |
Pfam | UHGV-0227382_42 | PF04233 | N/A | N/A | Phage Mu protein F like protein | Phage_Mu_F |
NCBIFam | UHGV-0227382_42 | TIGR01641.1 | N/A | N/A | minor capsid protein | N/A |
COG | UHGV-0227382_42 | COG2369 | N/A | N/A | N/A | N/A |
structural_annotation | UHGV-0227382_42 | PF04233,TIGR01641,COG2369 | N/A | N/A | N/A | N/A |
PHROG | UHGV-0227382_43 | phrog_328 | 190.6 | 0 | head maturation protease | head and packaging |
UniRef90 | UHGV-0227382_43 | UniRef90_R5HQP9 | 471.0 | 0 | Serine/arginine repetitive matrix protein 1 | N/A |
eggNOG-mapper | UHGV-0227382_43 | 1297617.JPJD01000049_gene1317 | 411.0 | 0 | Mu-like prophage I protein | N/A |
Pfam | UHGV-0227382_43 | PF10123 | N/A | N/A | Mu-like prophage I protein | Mu-like_Pro |
COG | UHGV-0227382_43 | COG4388 | N/A | N/A | Mu-like prophage I protein | N/A |