vOTU vOTU-014357

vOTU: vOTU-014357

Overview

Genome (FASTA) Annotation Track (GFF) Proteins (FASTA) Protein Annotation (TSV)

Cluster properties
vOTU ID	vOTU-014357
Number of genomes	4
Taxonomy (ICTV)	Bacteria → Firmicutes_A → Clostridia → Oscillospirales → Acutalibacteraceae → Ruminococcus_E → Ruminococcus_E bromii_B
Taxonomy (UHGV)	vFAM-00006 → vSUBFAM-00673 → vGENUS-00827 → vSUBGEN-36479 → vOTU-014357
Host lineage	Bacteria → Firmicutes_A → Clostridia → Oscillospirales → Acutalibacteraceae → Ruminococcus_E → Ruminococcus_E bromii_B
Host range breadth	Species
Lifestyle	lytic (Evidence: BACPHLIP)

Representative genome
Genome ID	UHGV-2022991
Biosample ID	SAMEA2579947
Genome length (bp)	24,748 bps
CheckV completeness	99.90% (High-quality)
CDS count	41
CDS density	95.26%
tRNA count	0
Integrase	No
Viral confidence	Confident

Host assignment details
Assignment method	CRISPR
CRISPR-predicted host lineage	Bacteria → Firmicutes_A → Clostridia → Oscillospirales → Acutalibacteraceae → Ruminococcus_E → Ruminococcus_E bromii_B	Total connections	763	Host agreement	86.11
PHIST-predicted host lineage	Bacteria → Firmicutes_A → Clostridia → Oscillospirales → Acutalibacteraceae → Ruminococcus_E → Ruminococcus_E bromii_B	Total connections	2	Host agreement	100

Representative genome content

Select to view: Genome Viewer Functional Annotation

Genome view (completeness: 99.9)

Functional Annotation

Reference	Gene ID	Reference ID	Bit-score	E-value	Information	Category
PHROG	UHGV-2022991_1	phrog_1914	145.9	2.29813e-43	N/A	unknown function
UniRef90	UHGV-2022991_1	UniRef90_A0A374NDM7	350.0	0	ImmA/IrrE family metallo-endopeptidase	N/A
eggNOG-mapper	UHGV-2022991_1	1160721.RBI_I01604	169.0	0	N/A	N/A
Pfam	UHGV-2022991_1	PF06114	N/A	N/A	IrrE N-terminal-like domain	Peptidase_M78
COG	UHGV-2022991_1	COG2856	N/A	N/A	Zn-dependent peptidase ImmA, M78 family	N/A
structural_annotation	UHGV-2022991_1	PF06114,COG2856	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_2	phrog_8	46.2	0.00000000000094	transcriptional regulator	transcription regulation
UniRef90	UHGV-2022991_2	UniRef90_UPI0015F3DE1D	190.0	0	helix-turn-helix domain-containing protein	N/A
eggNOG-mapper	UHGV-2022991_2	663278.Ethha_2423	73.2	0.00000000000000684	sequence-specific DNA binding	N/A
Pfam	UHGV-2022991_2	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
COG	UHGV-2022991_2	COG1396	N/A	N/A	Transcriptional regulator, contains XRE-family HTH domain	N/A
structural_annotation	UHGV-2022991_2	PF13560,MF_00535,NF041951,COG1476	N/A	N/A	N/A	N/A
UniRef90	UHGV-2022991_3	UniRef90_UPI000E51362F	129.0	5.12e-38	helix-turn-helix domain-containing protein	N/A
eggNOG-mapper	UHGV-2022991_3	411461.DORFOR_00030	52.0	0.000000043	Helix-turn-helix XRE-family like proteins	N/A
Pfam	UHGV-2022991_3	PF13443	N/A	N/A	Cro/C1-type HTH DNA-binding domain	HTH_26
structural_annotation	UHGV-2022991_3	PF13443,NF041951,COG1396	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_4	phrog_8684	95.4	8.7e-29	N/A	unknown function
UniRef90	UHGV-2022991_4	UniRef90_UPI000E48855B	248.0	0	YopX family protein	N/A
eggNOG-mapper	UHGV-2022991_4	1458852.A0A059T7V5_9CAUD	75.9	0.00000000000000112	YopX protein	N/A
Pfam	UHGV-2022991_4	PF09643	N/A	N/A	YopX protein	YopX
NCBIFam	UHGV-2022991_4	TIGR01671.1	N/A	N/A	phage conserved hypothetical protein TIGR01671	N/A
structural_annotation	UHGV-2022991_4	PF09643,TIGR01671	N/A	N/A	N/A	N/A
UniRef90	UHGV-2022991_5	UniRef90_UPI0015F48AC0	153.0	0	Lar family restriction alleviation protein	N/A
Pfam	UHGV-2022991_5	PF14354	N/A	N/A	Restriction alleviation protein Lar	Lar_restr_allev
structural_annotation	UHGV-2022991_5	PF14354,TIGR03655	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_7	phrog_4581	105.5	6e-31	terminase small subunit	head and packaging
UniRef90	UHGV-2022991_7	UniRef90_UPI0018A90D59	142.0	2.27e-39	HNH endonuclease	N/A
eggNOG-mapper	UHGV-2022991_7	1414720.CBYM010000040_gene1642	138.0	1.25e-38	HNH nucleases	N/A
Pfam	UHGV-2022991_7	PF13671	N/A	N/A	AAA domain	AAA_33
COG	UHGV-2022991_7	COG1403	N/A	N/A	5-methylcytosine-specific restriction endonuclease McrA	N/A
UniRef90	UHGV-2022991_8	UniRef90_A0A2N0ULT9	133.0	1e-39	DNA binding domain, excisionase family	N/A
eggNOG-mapper	UHGV-2022991_8	1283300.ATXB01000001_gene1737	45.8	0.0000097	DNA excision	N/A
Pfam	UHGV-2022991_8	PF12728	N/A	N/A	Helix-turn-helix domain	HTH_17
NCBIFam	UHGV-2022991_8	TIGR01764.1	N/A	N/A	excisionase family DNA-binding protein	N/A
COG	UHGV-2022991_8	COG3311	N/A	N/A	DNA-binding transcriptional regulator AlpA	N/A
structural_annotation	UHGV-2022991_8	PF12728,NF040990,COG3311	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_11	phrog_8470	211.6	0	N/A	unknown function
UniRef90	UHGV-2022991_11	UniRef90_UPI0018E45158	134.0	1.6e-30	PcfJ domain-containing protein	N/A
eggNOG-mapper	UHGV-2022991_11	641112.ACOK01000073_gene2870	110.0	1.61e-23	PcfJ-like protein	N/A
Pfam	UHGV-2022991_11	PF14284	N/A	N/A	PcfJ-like protein	PcfJ
structural_annotation	UHGV-2022991_11	PF14284	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_12	phrog_6963	44.3	0.0000000000029	N/A	unknown function
eggNOG-mapper	UHGV-2022991_12	641112.ACOK01000073_gene2872	77.8	2.47e-16	N/A	N/A
PHROG	UHGV-2022991_13	phrog_15609	44.4	0.0000000000023	N/A	unknown function
PHROG	UHGV-2022991_15	phrog_2118	122.6	3.3e-36	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-2022991_15	UniRef90_A0A374DVG7	230.0	0	HNH endonuclease	N/A
eggNOG-mapper	UHGV-2022991_15	610130.Closa_0730	144.0	6.33387e-43	HNH endonuclease	N/A
Pfam	UHGV-2022991_15	PF01844	N/A	N/A	HNH endonuclease	HNH
COG	UHGV-2022991_15	COG1403	N/A	N/A	5-methylcytosine-specific restriction endonuclease McrA	N/A
structural_annotation	UHGV-2022991_15	TIGR02646,COG1403	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_17	phrog_3584	147.9	6.86636e-44	replication initiation protein	DNA, RNA and nucleotide metabolism
eggNOG-mapper	UHGV-2022991_17	1235800.C819_00515	67.8	0.000000000123	N/A	N/A
structural_annotation	UHGV-2022991_17	PF21578,NF041486	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-2022991_18	394503.Ccel_3053	53.5	0.000000379	N/A	N/A
structural_annotation	UHGV-2022991_18	TIGR01636	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_19	phrog_119	71.9	8.8e-21	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-2022991_19	UniRef90_A0A373XNZ9	221.0	0	HNH endonuclease	N/A
eggNOG-mapper	UHGV-2022991_19	500633.CLOHIR_00362	119.0	7.08e-34	HNH endonuclease	N/A
Pfam	UHGV-2022991_19	PF01844	N/A	N/A	HNH endonuclease	HNH
COG	UHGV-2022991_19	COG1403	N/A	N/A	5-methylcytosine-specific restriction endonuclease McrA	N/A
PHROG	UHGV-2022991_20	phrog_1066	60.8	1.9e-18	N/A	unknown function
eggNOG-mapper	UHGV-2022991_20	931276.Cspa_c10130	67.8	0.000000000000925	N/A	N/A
PHROG	UHGV-2022991_21	phrog_9	310.5	0	terminase large subunit	head and packaging
UniRef90	UHGV-2022991_21	UniRef90_A0A373XNY0	1050.0	0	Terminase large subunit	N/A
eggNOG-mapper	UHGV-2022991_21	411468.CLOSCI_00551	682.0	0	COG COG4626 Phage terminase-like protein, large subunit	N/A
Pfam	UHGV-2022991_21	PF03354	N/A	N/A	Terminase large subunit, ATPase domain	TerL_ATPase
Pfam	UHGV-2022991_21	PF20441	N/A	N/A	Terminase large subunit, endonuclease domain	TerL_nuclease
COG	UHGV-2022991_21	COG4626	N/A	N/A	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	N/A
structural_annotation	UHGV-2022991_21	PF20441,PF03354,MF_04146,TIGR01547,COG4626	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_22	phrog_12	173.8	0	portal protein	head and packaging
UniRef90	UHGV-2022991_22	UniRef90_A0A373XNZ6	781.0	0	Phage portal protein	N/A
eggNOG-mapper	UHGV-2022991_22	411468.CLOSCI_00550	402.0	0	Phage portal protein	N/A
Pfam	UHGV-2022991_22	PF04860	N/A	N/A	Phage portal protein	Phage_portal
COG	UHGV-2022991_22	COG4695	N/A	N/A	Phage portal protein BeeE	N/A
structural_annotation	UHGV-2022991_22	PF04860,MF_04135,TIGR01537,COG4695	N/A	N/A	N/A	N/A
KOfam	UHGV-2022991_23	K01358	152.6	2.8026e-45	clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]	N/A
PHROG	UHGV-2022991_23	phrog_94	239.5	0	head maturation protease	head and packaging
UniRef90	UHGV-2022991_23	UniRef90_A0A373XPG0	467.0	0	ATP-dependent Clp protease proteolytic subunit	N/A
eggNOG-mapper	UHGV-2022991_23	1396.DJ87_978	251.0	0	Clp protease	N/A
Pfam	UHGV-2022991_23	PF00574	N/A	N/A	Clp protease	CLP_protease
COG	UHGV-2022991_23	COG0740	N/A	N/A	ATP-dependent protease ClpP, protease subunit	N/A
structural_annotation	UHGV-2022991_23	PF00574,MF_00444,NF011090,COG0740	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_24	phrog_10	128.0	1e-37	major head protein	head and packaging
UniRef90	UHGV-2022991_24	UniRef90_A0A373XLR3	723.0	0	Phage major capsid protein	N/A
eggNOG-mapper	UHGV-2022991_24	411468.CLOSCI_00548	380.0	0	Phage capsid family	N/A
Pfam	UHGV-2022991_24	PF05065	N/A	N/A	Phage capsid family	Phage_capsid
NCBIFam	UHGV-2022991_24	TIGR01554.2	N/A	N/A	phage major capsid protein	N/A
structural_annotation	UHGV-2022991_24	PF05065,MF_04119,TIGR01554,COG4653	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_25	phrog_5223	54.2	0.0000000000000019	neck protein	connector
UniRef90	UHGV-2022991_25	UniRef90_A0A174XIL0	95.1	1.72e-23	N/A	N/A
eggNOG-mapper	UHGV-2022991_25	411902.CLOBOL_03878	80.1	2.9e-18	N/A	N/A
PHROG	UHGV-2022991_26	phrog_1951	97.8	6.2e-29	head-tail adaptor	connector
UniRef90	UHGV-2022991_26	UniRef90_A0A373XMG4	219.0	0	Phage head-tail adapter protein	N/A
eggNOG-mapper	UHGV-2022991_26	1536769.P40081_01090	66.6	0.000000000000798	head-tail adaptor	N/A
NCBIFam	UHGV-2022991_26	TIGR01563.1	N/A	N/A	phage head closure protein	N/A
COG	UHGV-2022991_26	COG5614	N/A	N/A	Phage head-tail adaptor	N/A
structural_annotation	UHGV-2022991_26	PF05521,TIGR01563,COG5614	N/A	N/A	N/A	N/A
UniRef90	UHGV-2022991_27	UniRef90_UPI001A9B6FBF	164.0	0	HK97 gp10 family phage protein	N/A
eggNOG-mapper	UHGV-2022991_27	642492.Clole_0747	134.0	1.24e-38	N/A	N/A
structural_annotation	UHGV-2022991_27	TIGR01725	N/A	N/A	N/A	N/A
structural_annotation	UHGV-2022991_28	PF12691	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_29	phrog_885	136.0	2.29999e-40	major tail protein	tail
UniRef90	UHGV-2022991_29	UniRef90_Q894J4	163.0	0	Conserved protein	N/A
eggNOG-mapper	UHGV-2022991_29	1321814.HMPREF9089_00935	174.0	0	N/A	N/A
structural_annotation	UHGV-2022991_29	PF06488,TIGR01603,COG5437	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_30	phrog_1021	44.0	0.00000000000014	N/A	unknown function
PHROG	UHGV-2022991_32	phrog_23464	254.6	0	N/A	unknown function
UniRef90	UHGV-2022991_32	UniRef90_A0A1C6JGQ9	180.0	7.00649e-45	Phage-related minor tail protein	N/A
eggNOG-mapper	UHGV-2022991_32	1378168.N510_03078	180.0	1.4013e-45	Tail tape measure protein, TP901 family	N/A
COG	UHGV-2022991_32	COG5280	N/A	N/A	Phage-related minor tail protein	N/A
structural_annotation	UHGV-2022991_32	COG3941	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_33	phrog_33	58.0	2.6e-16	distal tail protein Dit	tail
UniRef90	UHGV-2022991_33	UniRef90_A0A1G5CPA2	110.0	1.79e-25	Phage-related protein	N/A
eggNOG-mapper	UHGV-2022991_33	1246.JMEA01000006_gene51	71.6	0.00000000000486	phage tail	N/A
COG	UHGV-2022991_33	COG4722	N/A	N/A	Phage-related protein YomH	N/A
structural_annotation	UHGV-2022991_33	PF20195,TIGR01633,COG4722	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_34	phrog_1067	144.6	5.89947e-43	minor head protein	head and packaging
UniRef90	UHGV-2022991_34	UniRef90_A0A348ZBV6	182.0	0	Prophage_tail domain-containing protein	N/A
eggNOG-mapper	UHGV-2022991_34	1160721.RBI_I01574	127.0	3.68e-29	Prophage endopeptidase tail	N/A
Pfam	UHGV-2022991_34	PF06605	N/A	N/A	Prophage endopeptidase tail	Prophage_tail
NCBIFam	UHGV-2022991_34	TIGR01665.1	N/A	N/A	phage tail spike protein	N/A
COG	UHGV-2022991_34	COG4926	N/A	N/A	Phage-related protein	N/A
structural_annotation	UHGV-2022991_34	PF14594,TIGR01665,COG4926	N/A	N/A	N/A	N/A
UniRef90	UHGV-2022991_35	UniRef90_A0A374N9Y2	316.0	0	N/A	N/A
Pfam	UHGV-2022991_35	PF10651	N/A	N/A	BppU N-terminal domain	BppU_N
structural_annotation	UHGV-2022991_35	PF10651,PF08931,TIGR02268	N/A	N/A	N/A	N/A
PHROG	UHGV-2022991_37	phrog_199	76.0	4.3e-22	holin	lysis
UniRef90	UHGV-2022991_37	UniRef90_A0A2N0ULW7	271.0	0	Holin	N/A
eggNOG-mapper	UHGV-2022991_37	1160721.RBI_I01565	143.0	8.72028e-42	Bacteriophage holin family	N/A
Pfam	UHGV-2022991_37	PF05105	N/A	N/A	Bacteriophage holin family	Phage_holin_4_1
NCBIFam	UHGV-2022991_37	TIGR01593.1	N/A	N/A	toxin secretion/phage lysis holin	N/A
COG	UHGV-2022991_37	COG4824	N/A	N/A	Phage-related holin (Lysis protein)	N/A
structural_annotation	UHGV-2022991_37	PF05105,TIGR01593,COG4824	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-2022991_38	411473.RUMCAL_02525	115.0	7.08e-32	N/A	N/A
KOfam	UHGV-2022991_39	K07273	199.5	0	acm; lysozyme	N/A
PHROG	UHGV-2022991_39	phrog_291	168.7	0	endolysin	lysis
UniRef90	UHGV-2022991_39	UniRef90_A0A373KPS8	541.0	0	PG_binding_1 domain-containing protein	N/A
eggNOG-mapper	UHGV-2022991_39	1120933.ATUY01000002_gene158	167.0	0	lysozyme activity	N/A
Pfam	UHGV-2022991_39	PF01183	N/A	N/A	Glycosyl hydrolases family 25	Glyco_hydro_25
Pfam	UHGV-2022991_39	PF01471	N/A	N/A	Putative peptidoglycan binding domain	PG_binding_1
COG	UHGV-2022991_39	COG3023	N/A	N/A	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	N/A
structural_annotation	UHGV-2022991_39	PF01183,PF01471,COG3757	N/A	N/A	N/A	N/A
KOfam	UHGV-2022991_40	K00571	55.0	0.0000000000000016	E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]	N/A
PHROG	UHGV-2022991_40	phrog_67	52.4	0.0000000000000089	DNA methyltransferase	other
UniRef90	UHGV-2022991_40	UniRef90_A0A843H832	86.3	1.01e-18	Site-specific DNA-methyltransferase	N/A
eggNOG-mapper	UHGV-2022991_40	877240.E1AC06_9CAUD	101.0	4.44e-25	helicase activity	N/A
PADLOC	UHGV-2022991_40	MTase_II_00157	56.1	0.0000000000000013	Type II methyltransferase	RM
KOfam	UHGV-2022991_41	K00571	91.6	1.2e-26	E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]	N/A
PHROG	UHGV-2022991_41	phrog_67	88.8	7.3e-26	DNA methyltransferase	other
UniRef90	UHGV-2022991_41	UniRef90_A0A412L7Z0	91.3	1.5e-22	Site-specific DNA-methyltransferase	N/A
eggNOG-mapper	UHGV-2022991_41	1154757.Q5C_06015	84.0	7.61e-19	DNA methylase	N/A
PADLOC	UHGV-2022991_41	MTase_II_00157	89.7	6.9e-26	Type II methyltransferase	RM
Pfam	UHGV-2022991_41	PF01555	N/A	N/A	DNA methylase	N6_N4_Mtase
COG	UHGV-2022991_41	COG2189	N/A	N/A	Adenine specific DNA methylase Mod	N/A

All viral genomes

ID	Representative?	Length (bps)	% GC Content	CheckV Completeness	geNomad Score
UHGV-2022991	Yes	24,748	40	100	1
UHGV-0068605	No	27,189	40	100	1
UHGV-1405935	No	27,189	40	100	1
UHGV-1492158	No	14,790	41	61	1