vOTU vOTU-027532

vOTU: vOTU-027532

Overview

Genome (FASTA) Annotation Track (GFF) Proteins (FASTA) Protein Annotation (TSV)

Cluster properties
vOTU ID	vOTU-027532
Number of genomes	2
Taxonomy (ICTV)	Bacteria → Firmicutes → Bacilli → Erysipelotrichales → Erysipelotrichaceae → Holdemania
Taxonomy (UHGV)	vFAM-00003 → vOTU-027532
Host lineage	Bacteria → Firmicutes → Bacilli → Erysipelotrichales → Erysipelotrichaceae → Holdemania → Holdemania filiformis
Host range breadth	Species
Lifestyle	temperate (Evidence: geNomad)

Representative genome
Genome ID	UHGV-0152258
Biosample ID	SAMN06112079
Genome length (bp)	44,156 bps
CheckV completeness	61.74% (Medium-quality)
CDS count	68
CDS density	91.76%
tRNA count	0
Integrase	No
Viral confidence	Confident

Host assignment details
Assignment method	CRISPR
CRISPR-predicted host lineage	Bacteria → Firmicutes → Bacilli → Erysipelotrichales → Erysipelotrichaceae → Holdemania → Holdemania filiformis	Total connections	22	Host agreement	81.82
PHIST-predicted host lineage	Bacteria → Firmicutes → Bacilli → Erysipelotrichales → Erysipelotrichaceae → Holdemania	Total connections	3	Host agreement	100

Representative genome content

Select to view: Genome Viewer Functional Annotation

Genome view (completeness: 61.74)

Functional Annotation

Reference	Gene ID	Reference ID	Bit-score	E-value	Information	Category
UniRef90	UHGV-0152258_2	UniRef90_UPI001897398F	202.0	0	CTP synthase	N/A
eggNOG-mapper	UHGV-0152258_2	1232447.BAHW02000005_gene154	54.7	0.0000000302	N/A	N/A
PHROG	UHGV-0152258_3	phrog_1129	73.4	2.3e-21	holin	lysis
UniRef90	UHGV-0152258_3	UniRef90_UPI00189AB2A3	167.0	0	phage holin family protein	N/A
eggNOG-mapper	UHGV-0152258_3	33035.JPJF01000043_gene995	62.8	0.00000000000887	Phage holin family Hol44, in holin superfamily V	N/A
Pfam	UHGV-0152258_3	PF16079	N/A	N/A	Phage holin family Hol44, in holin superfamily V	Phage_holin_5_2
structural_annotation	UHGV-0152258_3	PF06946	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_4	phrog_355	56.1	6.4e-16	nucleoside 2-deoxyribosyltransferase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_4	UniRef90_UPI000934E5E6	208.0	0	N/A	N/A
eggNOG-mapper	UHGV-0152258_4	999411.HMPREF1092_00897	125.0	2.69e-36	N/A	N/A
Pfam	UHGV-0152258_4	PF14359	N/A	N/A	N/A	DUF4406
structural_annotation	UHGV-0152258_4	PF14359	N/A	N/A	N/A	N/A
UniRef90	UHGV-0152258_5	UniRef90_UPI001F05C666	870.0	0	C40 family peptidase	N/A
eggNOG-mapper	UHGV-0152258_5	394503.Ccel_3272	114.0	1.15e-26	NLP P60 protein	N/A
COG	UHGV-0152258_5	COG0791	N/A	N/A	Cell wall-associated hydrolase, NlpC_P60 family	N/A
structural_annotation	UHGV-0152258_13	PF07703,NF038114,COG5501	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_14	phrog_32322	40.9	0.000000000034	N/A	unknown function
UniRef90	UHGV-0152258_14	UniRef90_UPI000933FFCD	194.0	0	PF13754 domain-containing protein	N/A
eggNOG-mapper	UHGV-0152258_14	1256908.HMPREF0373_00675	51.2	0.000000322	N/A	N/A
Pfam	UHGV-0152258_14	PF13754	N/A	N/A	N/A	Big_3_4
structural_annotation	UHGV-0152258_14	PF13754	N/A	N/A	N/A	N/A
KOfam	UHGV-0152258_15	K13276	65.0	5.9e-19	bpr; bacillopeptidase F [EC:3.4.21.-]	N/A
PHROG	UHGV-0152258_15	phrog_11157	208.1	0	N/A	unknown function
UniRef90	UHGV-0152258_15	UniRef90_UPI00093277E2	517.0	0	Ig-like domain-containing protein	N/A
eggNOG-mapper	UHGV-0152258_15	1286171.EAL2_c11220	251.0	0	amine dehydrogenase activity	N/A
Pfam	UHGV-0152258_15	PF17957	N/A	N/A	Bacterial Ig domain	Big_7
Pfam	UHGV-0152258_15	PF09136	N/A	N/A	Glucodextranase, domain B	Glucodextran_B
COG	UHGV-0152258_15	COG3391	N/A	N/A	DNA-binding beta-propeller fold protein YncE	N/A
structural_annotation	UHGV-0152258_15	PF09136,PF13205,PF13754,MF_04116,NF032891,COG2372,COG5456	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0152258_16	1298920.KI911353_gene4837	67.4	0.00000000000603	N/A	N/A
PHROG	UHGV-0152258_17	phrog_18725	40.1	0.000000000071	N/A	unknown function
eggNOG-mapper	UHGV-0152258_17	1235800.C819_00473	64.3	0.000000000175	N/A	N/A
PHROG	UHGV-0152258_18	phrog_13879	231.4	0	N/A	unknown function
eggNOG-mapper	UHGV-0152258_18	742740.HMPREF9474_03516	367.0	0	N/A	N/A
structural_annotation	UHGV-0152258_18	PF03256,PF16466,PF13550,MF_00813,NF033848,COG3500	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_19	phrog_1194	63.0	4.6e-18	N/A	unknown function
eggNOG-mapper	UHGV-0152258_19	742740.HMPREF9474_03515	67.4	0.00000000000145	N/A	N/A
structural_annotation	UHGV-0152258_19	PF20458,TIGR02126,COG3499	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_20	phrog_1535	103.8	0	tail length tape measure protein	tail
UniRef90	UHGV-0152258_20	UniRef90_A0A2V2YP26	122.0	1.64e-24	Phage-related protein	N/A
eggNOG-mapper	UHGV-0152258_20	428127.EUBDOL_01563	396.0	0	homoserine transmembrane transporter activity	N/A
COG	UHGV-0152258_20	COG1280	N/A	N/A	Threonine/homoserine/homoserine lactone efflux protein	N/A
structural_annotation	UHGV-0152258_20	PF20155,TIGR01760,COG3941	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0152258_21	1211844.CBLM010000023_gene987	51.6	0.000000314	N/A	N/A
structural_annotation	UHGV-0152258_23	PF16463,PF17892,MF_04116,TIGR02241,NF012211,COG5437	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152258_24	PF08873,COG5003	N/A	N/A	N/A	N/A
UniRef90	UHGV-0152258_25	UniRef90_A0A7G9WJZ3	76.3	0.0000000000000211	HK97 gp10 family phage protein	N/A
eggNOG-mapper	UHGV-0152258_25	1235800.C819_00481	54.3	0.000000875	N/A	N/A
structural_annotation	UHGV-0152258_25	TIGR01725	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152258_27	PF19586,TIGR01563,COG5614	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_30	phrog_247	229.8	0	major head protein	head and packaging
UniRef90	UHGV-0152258_30	UniRef90_UPI001BA5448B	301.0	0	major capsid protein	N/A
eggNOG-mapper	UHGV-0152258_30	33035.JPJF01000106_gene3132	341.0	0	N/A	N/A
structural_annotation	UHGV-0152258_30	PF20036,MF_04113,TIGR04387,COG4653	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152258_31	PF14265	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_32	phrog_64	172.2	0	portal protein	head and packaging
UniRef90	UHGV-0152258_32	UniRef90_UPI00189855AC	1002.0	0	phage portal protein	N/A
eggNOG-mapper	UHGV-0152258_32	428127.EUBDOL_01552	373.0	0	Phage portal protein, SPP1 Gp6-like	N/A
Pfam	UHGV-0152258_32	PF05133	N/A	N/A	Phage portal protein, SPP1 Gp6-like	Phage_prot_Gp6
structural_annotation	UHGV-0152258_32	PF05133,MF_04120,TIGR01538,COG5511	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_33	phrog_38	181.3	0	terminase large subunit	head and packaging
UniRef90	UHGV-0152258_33	UniRef90_A0A840CR02	113.0	4.94e-23	Putative phage terminase large subunit-like protein	N/A
eggNOG-mapper	UHGV-0152258_33	428127.EUBDOL_01551	348.0	0	chromosome segregation	N/A
NCBIFam	UHGV-0152258_33	TIGR01630.1	N/A	N/A	phage terminase large subunit	N/A
COG	UHGV-0152258_33	COG5410	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152258_33	PF17289,MF_04147,NF033889,COG5410,COG5362	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_39	phrog_5763	74.6	1.7e-22	N/A	unknown function
eggNOG-mapper	UHGV-0152258_39	999413.HMPREF1094_00199	90.5	5.46e-18	N/A	N/A
PHROG	UHGV-0152258_40	phrog_1281	140.5	6.8005e-42	N/A	unknown function
UniRef90	UHGV-0152258_40	UniRef90_UPI00093298D8	337.0	0	N/A	N/A
eggNOG-mapper	UHGV-0152258_40	1033744.CAEL01000026_gene1412	134.0	6.12e-38	N/A	N/A
Pfam	UHGV-0152258_40	PF13274	N/A	N/A	Antitoxin SocA-like, Panacea domain	SocA_Panacea
COG	UHGV-0152258_40	COG3600	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152258_40	PF13274,COG3600	N/A	N/A	N/A	N/A
KOfam	UHGV-0152258_41	K14060	112.0	7.1e-33	pinR; putative DNA-invertase from lambdoid prophage Rac	N/A
PHROG	UHGV-0152258_41	phrog_125	160.9	0	DNA invertase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_41	UniRef90_UPI00189A4482	403.0	0	recombinase family protein	N/A
eggNOG-mapper	UHGV-0152258_41	428127.EUBDOL_01535	199.0	0	resolvase	N/A
Pfam	UHGV-0152258_41	PF00239	N/A	N/A	Resolvase, N terminal domain	Resolvase
Pfam	UHGV-0152258_41	PF13518	N/A	N/A	Helix-turn-helix domain	HTH_28
COG	UHGV-0152258_41	COG1961	N/A	N/A	Site-specific DNA recombinase SpoIVCA/DNA invertase PinE	N/A
structural_annotation	UHGV-0152258_41	PF00239,PF02796,NF009949,COG1961	N/A	N/A	N/A	N/A
UniRef90	UHGV-0152258_43	UniRef90_UPI001897CA7D	240.0	0	single-stranded DNA-binding protein	N/A
Pfam	UHGV-0152258_43	PF00436	N/A	N/A	Single-strand binding protein family	SSB
COG	UHGV-0152258_43	COG0629	N/A	N/A	Single-stranded DNA-binding protein	N/A
PHROG	UHGV-0152258_44	phrog_173	115.1	6.6e-34	nucleoside triphosphate pyrophosphohydrolase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_44	UniRef90_UPI00189B458A	347.0	0	dUTP diphosphatase	N/A
eggNOG-mapper	UHGV-0152258_44	1352230.S6AVW3_9CAUD	87.0	3.77e-19	dCTP diphosphatase activity	N/A
Pfam	UHGV-0152258_44	PF08761	N/A	N/A	dUTPase	dUTPase_2
structural_annotation	UHGV-0152258_44	PF08761,COG4508	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152258_45	PF04545,TIGR01636	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_46	phrog_24386	108.0	9.4e-32	N/A	unknown function
eggNOG-mapper	UHGV-0152258_46	511680.BUTYVIB_00647	102.0	3.74e-26	COG NOG28949 non supervised orthologous group	N/A
COG	UHGV-0152258_46	COG0241	N/A	N/A	Histidinol phosphatase/D-glycero-mannoheptose bisphosphatephosphatase, HAD superfamily	N/A
PHROG	UHGV-0152258_48	phrog_2245	97.9	8.6e-29	nucleoside triphosphate pyrophosphohydrolase	other
eggNOG-mapper	UHGV-0152258_48	293826.Amet_2596	78.6	6.47e-16	N/A	N/A
KOfam	UHGV-0152258_50	K00390	86.0	2.5e-25	cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]	N/A
PHROG	UHGV-0152258_50	phrog_424	134.8	1.4e-40	phosphoadenosine phosphosulfate reductase	moron, auxiliary metabolic gene and host takeover
UniRef90	UHGV-0152258_50	UniRef90_UPI0009327EF4	712.0	0	phosphoadenosine phosphosulfate reductase family protein	N/A
eggNOG-mapper	UHGV-0152258_50	1151292.QEW_4547	104.0	1.17e-22	N/A	N/A
Pfam	UHGV-0152258_50	PF01507	N/A	N/A	Phosphoadenosine phosphosulfate reductase family	PAPS_reduct
COG	UHGV-0152258_50	COG0175	N/A	N/A	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	N/A
structural_annotation	UHGV-0152258_50	PF01507,MF_00063,NF006327,COG0175	N/A	N/A	N/A	N/A
KOfam	UHGV-0152258_51	K00558	219.5	0	DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]	N/A
PHROG	UHGV-0152258_51	phrog_116	260.4	0	DNA methyltransferase	other
UniRef90	UHGV-0152258_51	UniRef90_UPI0009329361	1017.0	0	DNA cytosine methyltransferase	N/A
eggNOG-mapper	UHGV-0152258_51	1235800.C819_02255	658.0	0	C-5 cytosine-specific DNA methylase	N/A
PADLOC	UHGV-0152258_51	MTase_II_00020	105.2	1.3e-32	Type II methyltransferase	RM
Pfam	UHGV-0152258_51	PF00145	N/A	N/A	C-5 cytosine-specific DNA methylase	DNA_methylase
COG	UHGV-0152258_51	COG0270	N/A	N/A	DNA-cytosine methylase	N/A
structural_annotation	UHGV-0152258_51	PF00145,MF_00351,TIGR00675,COG0270	N/A	N/A	N/A	N/A
KOfam	UHGV-0152258_53	K03111	128.9	7.5e-38	ssb; single-strand DNA-binding protein	N/A
PHROG	UHGV-0152258_53	phrog_44	136.2	2.6e-40	single strand DNA binding protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_53	UniRef90_UPI000933C359	296.0	0	single-stranded DNA-binding protein	N/A
eggNOG-mapper	UHGV-0152258_53	1211819.CALK01000023_gene1688	171.0	0	Single-stranded DNA-binding protein	N/A
Pfam	UHGV-0152258_53	PF00436	N/A	N/A	Single-strand binding protein family	SSB
NCBIFam	UHGV-0152258_53	TIGR00621.2	N/A	N/A	single-stranded DNA-binding protein	N/A
COG	UHGV-0152258_53	COG0629	N/A	N/A	Single-stranded DNA-binding protein	N/A
HAMAP	UHGV-0152258_53	MF_00984	N/A	N/A	Single-stranded DNA-binding protein	N/A
structural_annotation	UHGV-0152258_53	PF00436,MF_00984,NF005580,COG0629	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_57	phrog_19458	255.4	0	primase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_57	UniRef90_UPI0010565CFE	282.0	0	ImmA/IrrE family metallo-endopeptidase	N/A
eggNOG-mapper	UHGV-0152258_57	411459.RUMOBE_01108	294.0	0	N/A	N/A
COG	UHGV-0152258_57	COG4227	N/A	N/A	Antirestriction protein ArdC	N/A
PHROG	UHGV-0152258_58	phrog_2514	82.5	6.6e-24	DnaD-like helicase loader	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_58	UniRef90_A0A318KSV9	98.2	8.71e-21	DnaD/phage-associated family protein	N/A
eggNOG-mapper	UHGV-0152258_58	428127.EUBDOL_01512	148.0	2.59001e-40	DnaD domain protein	N/A
COG	UHGV-0152258_58	COG3935	N/A	N/A	DNA replication protein DnaD	N/A
structural_annotation	UHGV-0152258_58	PF10771,MF_01177,TIGR01714,COG0640	N/A	N/A	N/A	N/A
KOfam	UHGV-0152258_59	K01160	61.9	1.9e-17	rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]	N/A
PHROG	UHGV-0152258_59	phrog_140	142.0	3.00018e-42	RusA-like Holliday junction resolvase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_59	UniRef90_UPI001899EB33	261.0	0	RusA family crossover junction endodeoxyribonuclease	N/A
eggNOG-mapper	UHGV-0152258_59	857293.CAAU_0790	143.0	3.62936e-42	Endodeoxyribonuclease RusA	N/A
Pfam	UHGV-0152258_59	PF05866	N/A	N/A	Endodeoxyribonuclease RusA	RusA
COG	UHGV-0152258_59	COG4570	N/A	N/A	Holliday junction resolvase RusA (prophage-encoded endonuclease)	N/A
structural_annotation	UHGV-0152258_59	PF05866,NF007305,COG4570	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_60	phrog_997	48.1	0.0000000000002	replication terminator	DNA, RNA and nucleotide metabolism
KOfam	UHGV-0152258_61	K07455	301.1	0	recT; recombination protein RecT	N/A
PHROG	UHGV-0152258_61	phrog_148	284.9	0	RecT-like ssDNA annealing protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_61	UniRef90_A0A412G4J9	528.0	0	Recombinase RecT	N/A
eggNOG-mapper	UHGV-0152258_61	1226322.HMPREF1545_00015	360.0	0	RecT family	N/A
Pfam	UHGV-0152258_61	PF03837	N/A	N/A	RecT family	RecT
NCBIFam	UHGV-0152258_61	TIGR00616.1	N/A	N/A	recombinase, phage RecT family	N/A
COG	UHGV-0152258_61	COG3723	N/A	N/A	Recombinational DNA repair protein RecT	N/A
structural_annotation	UHGV-0152258_61	PF03837,NF007351,COG3723	N/A	N/A	N/A	N/A
PHROG	UHGV-0152258_62	phrog_434	328.5	0	RecE-like recombination exonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152258_62	UniRef90_UPI001F353DC5	637.0	0	YqaJ viral recombinase family protein	N/A
eggNOG-mapper	UHGV-0152258_62	428125.CLOLEP_01823	285.0	0	YqaJ viral recombinase family	N/A
Pfam	UHGV-0152258_62	PF09588	N/A	N/A	YqaJ-like viral recombinase domain	YqaJ
NCBIFam	UHGV-0152258_62	TIGR03033.1	N/A	N/A	putative phage-type endonuclease	N/A
COG	UHGV-0152258_62	COG5377	N/A	N/A	Phage-related protein, predicted endonuclease	N/A
structural_annotation	UHGV-0152258_62	PF09588,MF_03030,TIGR03033,COG5377	N/A	N/A	N/A	N/A
UniRef90	UHGV-0152258_65	UniRef90_UPI001899E818	324.0	0	glucosaminidase domain-containing protein	N/A
Pfam	UHGV-0152258_65	PF01832	N/A	N/A	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	Glucosaminidase
COG	UHGV-0152258_65	COG0791	N/A	N/A	Cell wall-associated hydrolase, NlpC_P60 family	N/A
structural_annotation	UHGV-0152258_65	PF01832,NF038016,COG1705	N/A	N/A	N/A	N/A
UniRef90	UHGV-0152258_66	UniRef90_UPI00093363A0	179.0	0	helix-turn-helix domain-containing protein	N/A
Pfam	UHGV-0152258_66	PF12728	N/A	N/A	Helix-turn-helix domain	HTH_17
PHROG	UHGV-0152258_67	phrog_8	55.0	0.0000000000000023	transcriptional regulator	transcription regulation
UniRef90	UHGV-0152258_67	UniRef90_UPI001898A404	121.0	5.98e-35	helix-turn-helix transcriptional regulator	N/A
eggNOG-mapper	UHGV-0152258_67	476272.RUMHYD_02827	89.7	4.9e-23	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	N/A
Pfam	UHGV-0152258_67	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
COG	UHGV-0152258_67	COG1974	N/A	N/A	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	N/A
structural_annotation	UHGV-0152258_67	PF01381,NF041951,COG1396	N/A	N/A	N/A	N/A
KOfam	UHGV-0152258_68	K22299	47.0	0.00000000000066	rghR; HTH-type transcriptional regulator, competence development regulator	N/A
PHROG	UHGV-0152258_68	phrog_8	73.9	3.3e-21	transcriptional regulator	transcription regulation
UniRef90	UHGV-0152258_68	UniRef90_UPI0009355DEA	208.0	0	helix-turn-helix domain-containing protein	N/A
eggNOG-mapper	UHGV-0152258_68	1304866.K413DRAFT_0834	82.8	3.1e-19	PFAM helix-turn-helix domain protein	N/A
Pfam	UHGV-0152258_68	PF13443	N/A	N/A	Cro/C1-type HTH DNA-binding domain	HTH_26
COG	UHGV-0152258_68	COG1974	N/A	N/A	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	N/A
structural_annotation	UHGV-0152258_68	PF01381,MF_00535,NF041951,COG1476	N/A	N/A	N/A	N/A

All viral genomes

ID	Representative?	Length (bps)	% GC Content	CheckV Completeness	geNomad Score
UHGV-0152258	Yes	44,156	42	62	1
UHGV-1522588	No	36,838	41	79	1