vOTU vOTU-027554

vOTU: vOTU-027554

Overview

Genome (FASTA) Annotation Track (GFF) Proteins (FASTA) Protein Annotation (TSV)

Cluster properties
vOTU ID	vOTU-027554
Number of genomes	2
Taxonomy (ICTV)
Taxonomy (UHGV)	vFAM-00004 → vSUBFAM-00118 → vGENUS-00957 → vOTU-027554
Host lineage	Bacteria → Firmicutes_A → Clostridia → Oscillospirales → Butyricicoccaceae → Agathobaculum
Host range breadth	Genus
Lifestyle	lytic (Evidence: BACPHLIP)

Representative genome
Genome ID	UHGV-0152830
Biosample ID	SAMN06110155
Genome length (bp)	33,360 bps
CheckV completeness	74.29% (Medium-quality)
CDS count	63
CDS density	87.56%
tRNA count	0
Integrase	No
Viral confidence	Confident

Host assignment details
Assignment method	CRISPR
CRISPR-predicted host lineage	Bacteria → Firmicutes_A → Clostridia → Oscillospirales → Butyricicoccaceae → Agathobaculum	Total connections	187	Host agreement	98.4
PHIST-predicted host lineage		Total connections		Host agreement

Representative genome content

Select to view: Genome Viewer Functional Annotation

Genome view (completeness: 74.29)

Functional Annotation

Reference	Gene ID	Reference ID	Bit-score	E-value	Information	Category
KOfam	UHGV-0152830_1	K07741	220.0	0	antB; anti-repressor protein	N/A
PHROG	UHGV-0152830_1	phrog_63	184.2	0	anti-repressor Ant	transcription regulation
UniRef90	UHGV-0152830_1	UniRef90_A0A7I8D1Y4	332.0	0	Putative P1-type antirepressor - phage associated	N/A
eggNOG-mapper	UHGV-0152830_1	1232443.BAIA02000079_gene53	327.0	0	AntA/AntB antirepressor	N/A
Pfam	UHGV-0152830_1	PF08346	N/A	N/A	AntA/AntB antirepressor	AntA
Pfam	UHGV-0152830_1	PF03374	N/A	N/A	Phage antirepressor protein KilAC domain	ANT
COG	UHGV-0152830_1	COG3561	N/A	N/A	Phage anti-repressor protein Ant	N/A
structural_annotation	UHGV-0152830_1	PF03374,PF08346,TIGR02681,COG3645,COG3561	N/A	N/A	N/A	N/A
KOfam	UHGV-0152830_3	K22300	70.7	3.1e-20	dicA; HTH-type transcriptional regulator, cell division transcriptional repressor	N/A
PHROG	UHGV-0152830_3	phrog_2967	63.2	2.6e-18	transcriptional regulator	transcription regulation
UniRef90	UHGV-0152830_3	UniRef90_A0A0U2UH00	83.6	6.61e-18	Xre family transcriptional regulator	N/A
eggNOG-mapper	UHGV-0152830_3	1444310.JANV01000024_gene1355	70.9	0.000000000000461	Peptidase S24-like	N/A
PADLOC	UHGV-0152830_3	retron_type_VI_hth_cluster2_1	47.8	0.00000000000039	N/A	Retron
Pfam	UHGV-0152830_3	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
COG	UHGV-0152830_3	COG1974	N/A	N/A	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	N/A
KOfam	UHGV-0152830_4	K07729	41.2	0.000000000033	K07729; putative transcriptional regulator	N/A
UniRef90	UHGV-0152830_4	UniRef90_UPI000F62C44C	81.3	6.07e-19	helix-turn-helix domain-containing protein	N/A
PADLOC	UHGV-0152830_4	retron_type_VI_hth_cluster2_1	41.2	0.000000000056	N/A	Retron
Pfam	UHGV-0152830_4	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
COG	UHGV-0152830_4	COG1476	N/A	N/A	DNA-binding transcriptional regulator, XRE-family HTH domain	N/A
structural_annotation	UHGV-0152830_4	PF01381,NF041951,COG1476	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152830_5	PF21441,TIGR04176,COG1846	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152830_6	COG3311	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0152830_8	596152.DesU5LDRAFT_1910	73.9	0.000000000000206	N/A	N/A
structural_annotation	UHGV-0152830_8	PF03787,TIGR02581,COG1604	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_11	phrog_253	127.3	1.1e-37	Mu Gam-like end protection	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152830_11	UniRef90_UPI00164A4E04	211.0	0	siphovirus Gp157 family protein	N/A
eggNOG-mapper	UHGV-0152830_11	1226322.HMPREF1545_04074	122.0	4.7e-33	Siphovirus Gp157	N/A
Pfam	UHGV-0152830_11	PF05565	N/A	N/A	Siphovirus Gp157	Sipho_Gp157
structural_annotation	UHGV-0152830_11	PF05565,NF002139	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_12	phrog_155	131.9	5e-39	Erf-like ssDNA annealing protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152830_12	UniRef90_A0A7U9PED5	221.0	0	ERF superfamily protein	N/A
eggNOG-mapper	UHGV-0152830_12	1304866.K413DRAFT_1196	221.0	0	ERF superfamily	N/A
Pfam	UHGV-0152830_12	PF04404	N/A	N/A	ERF superfamily	ERF
COG	UHGV-0152830_12	COG0629	N/A	N/A	Single-stranded DNA-binding protein	N/A
structural_annotation	UHGV-0152830_12	PF04404,TIGR00607,COG4712	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_13	phrog_72	48.8	0.0000000000001	NinB/ Orf homologous recombination mediator	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152830_13	UniRef90_A0A8D9PDS2	112.0	4.19e-28	NinB protein	N/A
eggNOG-mapper	UHGV-0152830_13	445972.ANACOL_01825	132.0	6.87e-37	N/A	N/A
structural_annotation	UHGV-0152830_13	PF05772	N/A	N/A	N/A	N/A
KOfam	UHGV-0152830_14	K07451	45.4	0.0000000000015	mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]	N/A
PHROG	UHGV-0152830_14	phrog_7370	56.2	6.1e-16	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152830_14	UniRef90_A0A845MWL0	210.0	0	HNHc domain-containing protein	N/A
eggNOG-mapper	UHGV-0152830_14	1232449.BAHV02000016_gene1841	78.6	1.41e-17	HNH nucleases	N/A
Pfam	UHGV-0152830_14	PF01844	N/A	N/A	HNH endonuclease	HNH
KOfam	UHGV-0152830_15	K03111	115.2	9.6e-34	ssb; single-strand DNA-binding protein	N/A
PHROG	UHGV-0152830_15	phrog_44	122.6	3.7e-36	single strand DNA binding protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152830_15	UniRef90_A0A417H728	201.0	0	Single-stranded DNA-binding protein	N/A
eggNOG-mapper	UHGV-0152830_15	1203606.HMPREF1526_02270	115.0	5.44e-31	Single-stranded DNA-binding protein	N/A
Pfam	UHGV-0152830_15	PF00436	N/A	N/A	Single-strand binding protein family	SSB
NCBIFam	UHGV-0152830_15	TIGR00621.2	N/A	N/A	single-stranded DNA-binding protein	N/A
COG	UHGV-0152830_15	COG0629	N/A	N/A	Single-stranded DNA-binding protein	N/A
HAMAP	UHGV-0152830_15	MF_00984	N/A	N/A	Single-stranded DNA-binding protein	N/A
structural_annotation	UHGV-0152830_15	PF00436,MF_00984,NF005241,COG0629	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_16	phrog_2514	84.2	1.4e-24	DnaD-like helicase loader	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152830_16	UniRef90_A0A2A6ZGI2	80.5	0.0000000000000214	HTH gntR-type domain-containing protein	N/A
eggNOG-mapper	UHGV-0152830_16	742733.HMPREF9469_01845	117.0	4.65e-29	N/A	N/A
structural_annotation	UHGV-0152830_16	PF10771,MF_01177,TIGR01610,COG0640	N/A	N/A	N/A	N/A
KOfam	UHGV-0152830_18	K01160	44.8	0.0000000000035	rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]	N/A
PHROG	UHGV-0152830_18	phrog_1682	85.4	8.7e-25	RusA-like Holliday junction resolvase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152830_18	UniRef90_A0A417H6W1	210.0	0	RusA family crossover junction endodeoxyribonuclease	N/A
eggNOG-mapper	UHGV-0152830_18	697281.Mahau_0558	129.0	5.89e-37	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC	N/A
COG	UHGV-0152830_18	COG4570	N/A	N/A	Holliday junction resolvase RusA (prophage-encoded endonuclease)	N/A
structural_annotation	UHGV-0152830_18	PF19595,NF007305,COG4570	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0152830_19	279238.Saro_2694	48.5	0.00000323	DNA (cytosine-5-)-methyltransferase activity	N/A
COG	UHGV-0152830_19	COG0270	N/A	N/A	DNA-cytosine methylase	N/A
PHROG	UHGV-0152830_20	phrog_3136	152.9	1.4013e-45	N/A	unknown function
UniRef90	UHGV-0152830_20	UniRef90_A0A329TS47	165.0	0	ASCH domain-containing protein	N/A
eggNOG-mapper	UHGV-0152830_20	1007096.BAGW01000031_gene120	57.8	0.000000137	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	N/A
COG	UHGV-0152830_20	COG4933	N/A	N/A	Predicted transcriptional regulator, contains an HTH and PUA-like domains	N/A
structural_annotation	UHGV-0152830_20	PF08819,MF_00684,NF008917,COG4933	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_22	phrog_22543	48.9	0.00000000000012	N/A	unknown function
UniRef90	UHGV-0152830_23	UniRef90_A0A8D9PDK2	51.6	0.00000209	Zinc-ribbon containing domain	N/A
PHROG	UHGV-0152830_24	phrog_599	45.7	0.0000000000014	Lar-like restriction alleviation protein	moron, auxiliary metabolic gene and host takeover
UniRef90	UHGV-0152830_24	UniRef90_A0A845MWR1	107.0	1.9e-29	Restriction alleviation protein, Lar family	N/A
Pfam	UHGV-0152830_24	PF14354	N/A	N/A	Restriction alleviation protein Lar	Lar_restr_allev
dbAPIS	UHGV-0152830_24	APIS033	N/A	N/A	Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin.	N/A
structural_annotation	UHGV-0152830_24	PF14354,NF007260	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_25	phrog_236	110.1	2.6e-32	nucleotide kinase	other
UniRef90	UHGV-0152830_25	UniRef90_A0A845MY30	174.0	0	N/A	N/A
eggNOG-mapper	UHGV-0152830_25	1033743.CAES01000020_gene3148	89.0	3.92e-21	N/A	N/A
Pfam	UHGV-0152830_25	PF11753	N/A	N/A	N/A	DUF3310
structural_annotation	UHGV-0152830_25	PF11753	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_26	phrog_774	51.8	0.000000000000018	N/A	unknown function
UniRef90	UHGV-0152830_26	UniRef90_U4KJB1	52.8	0.000000889	N/A	N/A
eggNOG-mapper	UHGV-0152830_26	1042156.CXIVA_01820	55.1	0.0000000289	N/A	N/A
PHROG	UHGV-0152830_28	phrog_25385	86.3	2.9e-25	N/A	unknown function
eggNOG-mapper	UHGV-0152830_28	748224.HMPREF9436_03077	84.0	2.02e-19	N/A	N/A
KOfam	UHGV-0152830_29	K03744	161.7	0	lemA; LemA protein	N/A
PHROG	UHGV-0152830_29	phrog_1383	140.1	1.10002e-41	virion structural protein	head and packaging
UniRef90	UHGV-0152830_29	UniRef90_A0A417TP98	326.0	0	LemA family protein	N/A
eggNOG-mapper	UHGV-0152830_29	742735.HMPREF9467_00879	174.0	0	LemA family	N/A
Pfam	UHGV-0152830_29	PF04011	N/A	N/A	LemA family	LemA
COG	UHGV-0152830_29	COG1704	N/A	N/A	Magnetosome formation protein MamQ, lipoprotein antigen LemA family	N/A
structural_annotation	UHGV-0152830_29	PF04011,NF040966,COG1704	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_30	phrog_3886	199.0	0	N/A	unknown function
eggNOG-mapper	UHGV-0152830_30	742735.HMPREF9467_00880	161.0	0	N/A	N/A
PHROG	UHGV-0152830_33	phrog_36	58.1	2e-16	transcriptional regulator	transcription regulation
COG	UHGV-0152830_33	COG1191	N/A	N/A	DNA-directed RNA polymerase specialized sigma subunit	N/A
structural_annotation	UHGV-0152830_33	PF07374,TIGR01636	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_34	phrog_99	64.3	1.5e-18	HNH endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0152830_34	UniRef90_UPI00195ADA30	134.0	2.06e-34	AP2 domain-containing protein	N/A
eggNOG-mapper	UHGV-0152830_34	246199.CUS_5638	116.0	1.38e-28	N/A	N/A
Pfam	UHGV-0152830_34	PF00847	N/A	N/A	AP2 domain	AP2
PHROG	UHGV-0152830_35	phrog_25567	48.8	0.0000000000001	N/A	unknown function
UniRef90	UHGV-0152830_35	UniRef90_UPI00164AED9E	113.0	1.7e-30	helix-turn-helix domain-containing protein	N/A
eggNOG-mapper	UHGV-0152830_35	1235798.C817_04600	67.8	0.000000000000296	N/A	N/A
structural_annotation	UHGV-0152830_35	NF040522,COG2944	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0152830_40	658659.HMPREF0983_00103	115.0	8.98e-31	N/A	N/A
structural_annotation	UHGV-0152830_40	PF18847	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152830_41	PF03869,NF010256	N/A	N/A	N/A	N/A
KOfam	UHGV-0152830_42	K07474	47.9	0.00000000000046	xtmA; phage terminase small subunit	N/A
PHROG	UHGV-0152830_42	phrog_51	59.8	1.8e-17	terminase small subunit	head and packaging
UniRef90	UHGV-0152830_42	UniRef90_A0A2V2FED9	231.0	0	Terminase small subunit	N/A
eggNOG-mapper	UHGV-0152830_42	702450.CUW_0530	103.0	8.08e-27	Terminase Small Subunit	N/A
Pfam	UHGV-0152830_42	PF03592	N/A	N/A	Terminase small subunit	Terminase_2
COG	UHGV-0152830_42	COG3728	N/A	N/A	Phage terminase, small subunit	N/A
structural_annotation	UHGV-0152830_42	PF03592,COG3728	N/A	N/A	N/A	N/A
KOfam	UHGV-0152830_43	K06909	231.5	0	xtmB; phage terminase large subunit	N/A
PHROG	UHGV-0152830_43	phrog_3717	205.9	0	terminase large subunit	head and packaging
UniRef90	UHGV-0152830_43	UniRef90_A0A417HVY4	974.0	0	PBSX family phage terminase large subunit	N/A
eggNOG-mapper	UHGV-0152830_43	445971.ANASTE_00711	515.0	0	Phage terminase, large subunit, PBSX family	N/A
Pfam	UHGV-0152830_43	PF04466	N/A	N/A	Phage terminase large subunit	Terminase_3
NCBIFam	UHGV-0152830_43	TIGR01547.1	N/A	N/A	PBSX family phage terminase large subunit	N/A
COG	UHGV-0152830_43	COG1783	N/A	N/A	Phage terminase large subunit	N/A
structural_annotation	UHGV-0152830_43	PF04466,MF_04145,TIGR01547,COG1783	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_44	phrog_156	251.3	0	portal protein	head and packaging
eggNOG-mapper	UHGV-0152830_44	1519439.JPJG01000060_gene1886	539.0	0	N/A	N/A
structural_annotation	UHGV-0152830_44	PF16510,MF_04120,TIGR01542,COG4695	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_47	phrog_35275	86.8	2.4e-25	N/A	unknown function
eggNOG-mapper	UHGV-0152830_47	693746.OBV_23910	99.0	2.39e-21	N/A	N/A
PHROG	UHGV-0152830_48	phrog_24113	48.9	0.00000000000009	N/A	unknown function
structural_annotation	UHGV-0152830_48	PF11133,COG5471	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_49	phrog_371	117.4	1.1e-34	major head protein	head and packaging
UniRef90	UHGV-0152830_49	UniRef90_UPI00164C0E21	515.0	0	Mu-like prophage major head subunit gpT family protein	N/A
eggNOG-mapper	UHGV-0152830_49	1226322.HMPREF1545_03848	281.0	0	N/A	N/A
Pfam	UHGV-0152830_49	PF10124	N/A	N/A	Mu-like prophage major head subunit gpT	Mu-like_gpT
structural_annotation	UHGV-0152830_49	PF05065,MF_04119,TIGR01554,COG4653	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_50	phrog_13046	53.0	0.0000000000000034	N/A	unknown function
eggNOG-mapper	UHGV-0152830_50	693746.OBV_23880	86.7	3.41e-18	N/A	N/A
structural_annotation	UHGV-0152830_50	PF20387	N/A	N/A	N/A	N/A
PHROG	UHGV-0152830_51	phrog_3287	127.4	6.1e-38	virion structural protein	head and packaging
eggNOG-mapper	UHGV-0152830_51	1232449.BAHV02000016_gene1816	413.0	0	N/A	N/A
structural_annotation	UHGV-0152830_51	PF11134,MF_01282,TIGR03300,COG5276	N/A	N/A	N/A	N/A
KOfam	UHGV-0152830_52	K16617	78.4	4.8e-23	COL13A; collagen type XIII alpha	N/A
PHROG	UHGV-0152830_52	phrog_819	132.1	2.6e-39	tail protein	tail
eggNOG-mapper	UHGV-0152830_52	1408437.JNJN01000030_gene1051	92.4	8.7e-18	cellulose 1,4-beta-cellobiosidase activity	N/A
Pfam	UHGV-0152830_52	PF01391	N/A	N/A	Collagen triple helix repeat (20 copies)	Collagen
COG	UHGV-0152830_52	COG5301	N/A	N/A	Phage-related tail fiber protein	N/A
PHROG	UHGV-0152830_53	phrog_24451	48.3	0.00000000000017	N/A	unknown function
eggNOG-mapper	UHGV-0152830_53	189425.PGRAT_24000	70.1	0.000000000000109	N/A	N/A
PHROG	UHGV-0152830_54	phrog_1382	48.2	0.000000000000093	N/A	unknown function
eggNOG-mapper	UHGV-0152830_54	743719.PaelaDRAFT_2420	51.6	0.0000000291	N/A	N/A
PHROG	UHGV-0152830_56	phrog_1863	75.5	1.7e-22	N/A	unknown function
UniRef90	UHGV-0152830_56	UniRef90_UPI001F223E8B	93.2	3.43e-23	hemolysin XhlA family protein	N/A
eggNOG-mapper	UHGV-0152830_56	1203606.HMPREF1526_02027	82.0	1.45e-19	N/A	N/A
PHROG	UHGV-0152830_57	phrog_297	45.0	0.0000000000017	holin	lysis
UniRef90	UHGV-0152830_57	UniRef90_A0A417HAK5	160.0	0	Phage holin	N/A
eggNOG-mapper	UHGV-0152830_57	1408437.JNJN01000039_gene392	104.0	1.98e-28	COG COG5546 Small integral membrane protein	N/A
Pfam	UHGV-0152830_57	PF04531	N/A	N/A	Bacteriophage holin	Phage_holin_1
NCBIFam	UHGV-0152830_57	TIGR01598.1	N/A	N/A	phage holin	N/A
COG	UHGV-0152830_57	COG5546	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0152830_57	COG5546	N/A	N/A	N/A	N/A
KOfam	UHGV-0152830_58	K01447	138.0	9.60002e-41	xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]	N/A
PHROG	UHGV-0152830_58	phrog_670	143.9	1.3004e-42	endolysin	lysis
UniRef90	UHGV-0152830_58	UniRef90_A0A417HAK3	273.0	0	N-acetylmuramoyl-L-alanine amidase	N/A
eggNOG-mapper	UHGV-0152830_58	97138.C820_00588	216.0	0	Ami_2	N/A
Pfam	UHGV-0152830_58	PF01510	N/A	N/A	N-acetylmuramoyl-L-alanine amidase	Amidase_2
COG	UHGV-0152830_58	COG5632	N/A	N/A	N-acetylmuramoyl-L-alanine amidase CwlA	N/A
structural_annotation	UHGV-0152830_58	PF01510,MF_04111,NF008758,COG5632	N/A	N/A	N/A	N/A
UniRef90	UHGV-0152830_59	UniRef90_UPI0004E194C7	78.2	1.03e-17	LuxR C-terminal-related transcriptional regulator	N/A
Pfam	UHGV-0152830_59	PF00196	N/A	N/A	Bacterial regulatory proteins, luxR family	GerE
structural_annotation	UHGV-0152830_59	PF04545,MF_00245,NF001067,COG2771	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0152830_61	1408437.JNJN01000043_gene805	121.0	3.26e-34	N/A	N/A
eggNOG-mapper	UHGV-0152830_62	476272.RUMHYD_01953	54.7	0.00000000694	N/A	N/A

All viral genomes

ID	Representative?	Length (bps)	% GC Content	CheckV Completeness	geNomad Score
UHGV-0152830	Yes	33,360	54	74	1
UHGV-1762729	No	13,585	55	30	1