vOTU vOTU-105287

vOTU: vOTU-105287

Overview

Genome (FASTA) Annotation Track (GFF) Proteins (FASTA) Protein Annotation (TSV)

Cluster properties
vOTU ID	vOTU-105287
Number of genomes	1
Taxonomy (ICTV)
Taxonomy (UHGV)	vFAM-00007 → vSUBFAM-00318 → vGENUS-06211 → vOTU-105287
Host lineage	Bacteria → Firmicutes_A → Clostridia → Lachnospirales → Lachnospiraceae → Mediterraneibacter
Host range breadth	Genus
Lifestyle	temperate (Evidence: integrase)

Representative genome
Genome ID	UHGV-0133523
Biosample ID	SAMN04209225
Genome length (bp)	32,633 bps
CheckV completeness	55.68% (Medium-quality)
CDS count	62
CDS density	87.41%
tRNA count	2
Integrase	Yes
Viral confidence	Confident

Host assignment details
Assignment method	CRISPR
CRISPR-predicted host lineage	Bacteria → Firmicutes_A → Clostridia → Lachnospirales → Lachnospiraceae → Mediterraneibacter	Total connections	53	Host agreement	81.13
PHIST-predicted host lineage		Total connections		Host agreement

Representative genome content

Select to view: Genome Viewer Functional Annotation

Genome view (completeness: 55.68)

Functional Annotation

Reference	Gene ID	Reference ID	Bit-score	E-value	Information	Category
KOfam	UHGV-0133523_1	K06400	337.8	0	spoIVCA; site-specific DNA recombinase	N/A
PHROG	UHGV-0133523_1	phrog_95	374.1	0	integrase	integration and excision
UniRef90	UHGV-0133523_1	UniRef90_A0A173SBX0	785.0	0	DNA-invertase hin	N/A
eggNOG-mapper	UHGV-0133523_1	411468.CLOSCI_00582	619.0	0	Recombinase	N/A
Pfam	UHGV-0133523_1	PF00239	N/A	N/A	Resolvase, N terminal domain	Resolvase
Pfam	UHGV-0133523_1	PF07508	N/A	N/A	Recombinase	Recombinase
Pfam	UHGV-0133523_1	PF13408	N/A	N/A	Recombinase zinc beta ribbon domain	Zn_ribbon_recom
COG	UHGV-0133523_1	COG1961	N/A	N/A	Site-specific DNA recombinase SpoIVCA/DNA invertase PinE	N/A
structural_annotation	UHGV-0133523_1	PF07508,PF00239,NF041201,COG1961	N/A	N/A	N/A	N/A
PHROG	UHGV-0133523_2	phrog_806	62.6	2.7e-18	N/A	unknown function
UniRef90	UHGV-0133523_2	UniRef90_UPI00189741AE	317.0	0	N/A	N/A
eggNOG-mapper	UHGV-0133523_2	697329.Rumal_0454	134.0	8.09e-35	N/A	N/A
Pfam	UHGV-0133523_2	PF13240	N/A	N/A	zinc-ribbon domain	zinc_ribbon_2
Pfam	UHGV-0133523_2	PF11611	N/A	N/A	N/A	DUF4352
structural_annotation	UHGV-0133523_2	PF11611,MF_00791,NF003967,COG2967	N/A	N/A	N/A	N/A
Pfam	UHGV-0133523_3	PF17854	N/A	N/A	FtsK alpha domain	FtsK_alpha
PHROG	UHGV-0133523_4	phrog_20886	62.0	5.6e-18	N/A	unknown function
structural_annotation	UHGV-0133523_4	PF06114,COG2856	N/A	N/A	N/A	N/A
KOfam	UHGV-0133523_5	K22300	45.5	0.0000000000014	dicA; HTH-type transcriptional regulator, cell division transcriptional repressor	N/A
PHROG	UHGV-0133523_5	phrog_8	64.5	2.2e-18	transcriptional regulator	transcription regulation
UniRef90	UHGV-0133523_5	UniRef90_A0A415D4V1	181.0	0	XRE family transcriptional regulator	N/A
eggNOG-mapper	UHGV-0133523_5	476272.RUMHYD_02826	92.8	1.52e-22	TRANSCRIPTIONal	N/A
Pfam	UHGV-0133523_5	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
COG	UHGV-0133523_5	COG1476	N/A	N/A	DNA-binding transcriptional regulator, XRE-family HTH domain	N/A
structural_annotation	UHGV-0133523_5	PF12844,MF_00535,NF041951,COG1476	N/A	N/A	N/A	N/A
PHROG	UHGV-0133523_6	phrog_8	49.4	0.000000000000085	transcriptional regulator	transcription regulation
UniRef90	UHGV-0133523_6	UniRef90_UPI001898A404	101.0	1.39e-26	helix-turn-helix transcriptional regulator	N/A
eggNOG-mapper	UHGV-0133523_6	476272.RUMHYD_02827	90.1	1.29e-22	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	N/A
Pfam	UHGV-0133523_6	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
COG	UHGV-0133523_6	COG1974	N/A	N/A	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	N/A
PHROG	UHGV-0133523_9	phrog_463	253.4	0	anti-repressor	transcription regulation
UniRef90	UHGV-0133523_9	UniRef90_UPI0018972D4E	384.0	0	ORF6C domain-containing protein	N/A
eggNOG-mapper	UHGV-0133523_9	596315.HMPREF0634_0237	197.0	0	BRO family, N-terminal domain protein	N/A
Pfam	UHGV-0133523_9	PF02498	N/A	N/A	BRO family, N-terminal domain	Bro-N
Pfam	UHGV-0133523_9	PF10552	N/A	N/A	ORF6C domain	ORF6C
COG	UHGV-0133523_9	COG3617	N/A	N/A	Prophage antirepressor	N/A
structural_annotation	UHGV-0133523_9	PF10552,PF02498,TIGR02681,COG3617	N/A	N/A	N/A	N/A
PHROG	UHGV-0133523_10	phrog_3502	45.1	0.0000000000019	N/A	unknown function
UniRef90	UHGV-0133523_10	UniRef90_A0A6L5X328	59.7	0.000000000462	MarR family transcriptional regulator	N/A
eggNOG-mapper	UHGV-0133523_10	1499683.CCFF01000013_gene198	56.6	0.000000000883	LexA DNA binding domain	N/A
Pfam	UHGV-0133523_10	PF04703	N/A	N/A	FaeA-like protein	FaeA
COG	UHGV-0133523_10	COG1974	N/A	N/A	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	N/A
structural_annotation	UHGV-0133523_10	PF01726,MF_00732,TIGR02944,COG1321	N/A	N/A	N/A	N/A
KOfam	UHGV-0133523_12	K19171	116.2	2.5e-34	dndD; DNA sulfur modification protein DndD	N/A
PHROG	UHGV-0133523_12	phrog_77	196.2	0	SbcC-like subunit of palindrome specific endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0133523_12	UniRef90_A0A173SB93	573.0	0	Chromosome segregation protein	N/A
eggNOG-mapper	UHGV-0133523_12	1121342.AUCO01000012_gene1723	206.0	0	nuclear chromosome segregation	N/A
PADLOC	UHGV-0133523_12	AAA_15	58.4	3.9e-16	N/A	N/A
Pfam	UHGV-0133523_12	PF13476	N/A	N/A	AAA domain	AAA_23
COG	UHGV-0133523_12	COG1196	N/A	N/A	Chromosome segregation ATPase Smc	N/A
structural_annotation	UHGV-0133523_12	PF02463,MF_00449,NF041034,COG0419	N/A	N/A	N/A	N/A
PHROG	UHGV-0133523_14	phrog_2185	324.5	0	RecT-like ssDNA annealing protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0133523_14	UniRef90_A0A173SDT4	538.0	0	RecT family	N/A
eggNOG-mapper	UHGV-0133523_14	658655.HMPREF0988_00886	412.0	0	N/A	N/A
Pfam	UHGV-0133523_14	PF03837	N/A	N/A	RecT family	RecT
structural_annotation	UHGV-0133523_14	NF007351,COG3723	N/A	N/A	N/A	N/A
KOfam	UHGV-0133523_15	K06940	56.3	7.3e-16	N/A	N/A
PHROG	UHGV-0133523_15	phrog_32498	154.1	0	N/A	unknown function
UniRef90	UHGV-0133523_15	UniRef90_A0A415D557	256.0	0	YkgJ family cysteine cluster protein	N/A
eggNOG-mapper	UHGV-0133523_15	476272.RUMHYD_03327	125.0	3.18e-35	Putative zinc- or iron-chelating domain	N/A
Pfam	UHGV-0133523_15	PF03692	N/A	N/A	Putative zinc- or iron-chelating domain	CxxCxxCC
PHROG	UHGV-0133523_16	phrog_392	54.0	0.0000000000000039	metal-dependent hydrolase	other
UniRef90	UHGV-0133523_16	UniRef90_A0A2X3IGT0	66.2	0.000000000000435	Metallo-beta-lactamase domain protein	N/A
eggNOG-mapper	UHGV-0133523_16	658655.HMPREF0988_00883	90.1	1.62e-23	May be involved in the transport of PQQ or its precursor to the periplasm	N/A
COG	UHGV-0133523_16	COG1235	N/A	N/A	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase	N/A
PHROG	UHGV-0133523_17	phrog_392	95.5	8.1e-28	metal-dependent hydrolase	other
UniRef90	UHGV-0133523_17	UniRef90_A0A415D4T3	290.0	0	Lactamase_B domain-containing protein	N/A
eggNOG-mapper	UHGV-0133523_17	658655.HMPREF0988_00882	236.0	0	Metallo-beta-lactamase superfamily	N/A
COG	UHGV-0133523_17	COG1235	N/A	N/A	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase	N/A
structural_annotation	UHGV-0133523_17	PF02112,MF_00457,NF041851,COG2220	N/A	N/A	N/A	N/A
KOfam	UHGV-0133523_18	K03111	144.4	1.19951e-42	ssb; single-strand DNA-binding protein	N/A
PHROG	UHGV-0133523_18	phrog_44	148.6	3.36312e-44	single strand DNA binding protein	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0133523_18	UniRef90_A0A415D4W7	247.0	0	Single-stranded DNA-binding protein	N/A
eggNOG-mapper	UHGV-0133523_18	411460.RUMTOR_02590	222.0	0	N/A	N/A
Pfam	UHGV-0133523_18	PF00436	N/A	N/A	Single-strand binding protein family	SSB
NCBIFam	UHGV-0133523_18	TIGR00621.2	N/A	N/A	single-stranded DNA-binding protein	N/A
COG	UHGV-0133523_18	COG0629	N/A	N/A	Single-stranded DNA-binding protein	N/A
HAMAP	UHGV-0133523_18	MF_00984	N/A	N/A	Single-stranded DNA-binding protein	N/A
structural_annotation	UHGV-0133523_18	PF00436,MF_00984,NF005580,COG0629	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0133523_21	476272.RUMHYD_02840	50.4	0.00000378	N/A	N/A
structural_annotation	UHGV-0133523_21	PF19962,COG1579	N/A	N/A	N/A	N/A
PHROG	UHGV-0133523_22	phrog_3490	129.8	1.4e-38	ERCC4-type nuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0133523_22	UniRef90_A0A173SAL3	374.0	0	ERCC4 domain-containing protein	N/A
eggNOG-mapper	UHGV-0133523_22	1232453.BAIF02000057_gene1143	217.0	0	N/A	N/A
Pfam	UHGV-0133523_22	PF02732	N/A	N/A	ERCC4 domain	ERCC4
structural_annotation	UHGV-0133523_22	PF02732,NF040956,COG1948	N/A	N/A	N/A	N/A
PHROG	UHGV-0133523_23	phrog_5708	239.1	0	DnaD-like helicase loader	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0133523_23	UniRef90_UPI001D1B9EE5	214.0	0	DnaD domain protein	N/A
eggNOG-mapper	UHGV-0133523_23	1391647.AVSV01000022_gene2531	185.0	0	DnaD domain protein	N/A
COG	UHGV-0133523_23	COG3935	N/A	N/A	DNA replication protein DnaD	N/A
structural_annotation	UHGV-0133523_23	PF09681,TIGR01714	N/A	N/A	N/A	N/A
KOfam	UHGV-0133523_24	K17680	116.3	1.10001e-40	PEO1; twinkle protein [EC:5.6.2.3]	N/A
PHROG	UHGV-0133523_24	phrog_19	192.2	0	DnaB-like replicative helicase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0133523_24	UniRef90_UPI0018977FCD	1114.0	0	AAA family ATPase	N/A
eggNOG-mapper	UHGV-0133523_24	1232453.BAIF02000057_gene1145	956.0	0	DNA replication initiation	N/A
Pfam	UHGV-0133523_24	PF13481	N/A	N/A	AAA domain	AAA_25
COG	UHGV-0133523_24	COG1241	N/A	N/A	DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family	N/A
structural_annotation	UHGV-0133523_24	PF03796,PF16793,MF_01498,MF_00700,NF004109,NF040562,COG0305,COG1467	N/A	N/A	N/A	N/A
UniRef90	UHGV-0133523_28	UniRef90_UPI00129E4C6A	53.5	0.00000196	N/A	N/A
KOfam	UHGV-0133523_30	K00390	86.2	3.4e-26	cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]	N/A
PHROG	UHGV-0133523_30	phrog_424	92.8	1.5e-27	phosphoadenosine phosphosulfate reductase	moron, auxiliary metabolic gene and host takeover
UniRef90	UHGV-0133523_30	UniRef90_A0A373SW63	729.0	0	PAPS_reduct domain-containing protein	N/A
eggNOG-mapper	UHGV-0133523_30	1235800.C819_02256	614.0	0	Phosphoadenosine phosphosulfate reductase family	N/A
Pfam	UHGV-0133523_30	PF01507	N/A	N/A	Phosphoadenosine phosphosulfate reductase family	PAPS_reduct
COG	UHGV-0133523_30	COG0175	N/A	N/A	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	N/A
structural_annotation	UHGV-0133523_30	PF01507,MF_00063,TIGR00434,COG0175	N/A	N/A	N/A	N/A
UniRef90	UHGV-0133523_33	UniRef90_UPI001E530297	129.0	3.12e-33	type I restriction-modification system subunit M N-terminal domain-containing protein	N/A
structural_annotation	UHGV-0133523_34	PF17400	N/A	N/A	N/A	N/A
PHROG	UHGV-0133523_36	phrog_9822	163.1	0	N/A	unknown function
PHROG	UHGV-0133523_38	phrog_25456	71.5	1.4e-21	N/A	unknown function
PHROG	UHGV-0133523_39	phrog_15198	43.0	0.000000000008	N/A	unknown function
UniRef90	UHGV-0133523_39	UniRef90_A0A416P6G8	188.0	0	N/A	N/A
eggNOG-mapper	UHGV-0133523_39	1256908.HMPREF0373_00667	96.7	1.73e-24	N/A	N/A
Pfam	UHGV-0133523_39	PF04448	N/A	N/A	N/A	DUF551
eggNOG-mapper	UHGV-0133523_40	887325.HMPREF0381_0090	100.0	1.75e-26	N/A	N/A
KOfam	UHGV-0133523_41	K22300	61.6	1.8e-17	dicA; HTH-type transcriptional regulator, cell division transcriptional repressor	N/A
PHROG	UHGV-0133523_41	phrog_8	61.2	2.6e-17	transcriptional regulator	transcription regulation
UniRef90	UHGV-0133523_41	UniRef90_UPI0018A9016D	115.0	9.3e-30	N/A	N/A
eggNOG-mapper	UHGV-0133523_41	1304880.JAGB01000002_gene2045	73.2	0.0000000000000169	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	N/A
Pfam	UHGV-0133523_41	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
Pfam	UHGV-0133523_41	PF04448	N/A	N/A	N/A	DUF551
COG	UHGV-0133523_41	COG1974	N/A	N/A	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	N/A
PHROG	UHGV-0133523_42	phrog_924	45.5	0.0000000000016	N/A	unknown function
UniRef90	UHGV-0133523_42	UniRef90_A0A373MXP0	231.0	0	N/A	N/A
eggNOG-mapper	UHGV-0133523_42	411462.DORLON_00804	50.4	0.00000206	N/A	N/A
Pfam	UHGV-0133523_42	PF04448	N/A	N/A	N/A	DUF551
PHROG	UHGV-0133523_43	phrog_20593	55.6	8.1e-16	N/A	unknown function
PHROG	UHGV-0133523_44	phrog_22292	82.9	2e-25	N/A	unknown function
KOfam	UHGV-0133523_48	K01520	61.7	1.2e-17	dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]	N/A
PHROG	UHGV-0133523_48	phrog_135	82.7	4.6e-24	dUTPase	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0133523_48	UniRef90_A0A373KP38	181.0	0	Deoxyuridine 5'-triphosphate nucleotidohydrolase	N/A
eggNOG-mapper	UHGV-0133523_48	1236976.JCM16418_5019	171.0	0	dUTPase	N/A
Pfam	UHGV-0133523_48	PF00692	N/A	N/A	dUTPase	dUTPase
COG	UHGV-0133523_48	COG0756	N/A	N/A	dUTP pyrophosphatase (dUTPase)	N/A
structural_annotation	UHGV-0133523_48	PF00692,MF_00116,TIGR00576,COG0756	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0133523_53	397290.C810_01347	48.5	0.00000079	N/A	N/A
structural_annotation	UHGV-0133523_53	PF18267	N/A	N/A	N/A	N/A
KOfam	UHGV-0133523_55	K07727	43.6	0.0000000000076	K07727; putative transcriptional regulator	N/A
UniRef90	UHGV-0133523_55	UniRef90_A0A3E2WG07	144.0	1.44334e-43	XRE family transcriptional regulator	N/A
eggNOG-mapper	UHGV-0133523_55	1235790.C805_00736	122.0	8.66e-36	Transcriptional regulator	N/A
Pfam	UHGV-0133523_55	PF13443	N/A	N/A	Cro/C1-type HTH DNA-binding domain	HTH_26
COG	UHGV-0133523_55	COG3655	N/A	N/A	DNA-binding transcriptional regulator, XRE family	N/A
structural_annotation	UHGV-0133523_55	PF13443,NF000090,COG3655	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0133523_56	658655.HMPREF0988_00895	99.0	1.4e-23	N/A	N/A
structural_annotation	UHGV-0133523_56	PF16677	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0133523_57	PF13069	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0133523_59	PF06004,NF033216,COG4568	N/A	N/A	N/A	N/A

All viral genomes

ID	Representative?	Length (bps)	% GC Content	CheckV Completeness	geNomad Score
UHGV-0133523	Yes	32,633	39	56	1