vOTU vOTU-161133

vOTU: vOTU-161133

Overview

Genome (FASTA) Annotation Track (GFF) Proteins (FASTA) Protein Annotation (TSV)

Cluster properties
vOTU ID	vOTU-161133
Number of genomes	1
Taxonomy (ICTV)	Bacteria → Firmicutes_A → Clostridia → Lachnospirales → Lachnospiraceae → Roseburia → Roseburia hominis
Taxonomy (UHGV)	vFAM-00007 → vSUBFAM-00090 → vGENUS-00263 → vOTU-161133
Host lineage	Bacteria → Firmicutes_A → Clostridia → Lachnospirales → Lachnospiraceae → Roseburia
Host range breadth	Genus
Lifestyle	lytic (Evidence: BACPHLIP)

Representative genome
Genome ID	UHGV-0034604
Biosample ID	SAMEA11460265
Genome length (bp)	46,025 bps
CheckV completeness	76.72% (Medium-quality)
CDS count	73
CDS density	84.29%
tRNA count	5
Integrase	No
Viral confidence	Confident

Host assignment details
Assignment method	CRISPR
CRISPR-predicted host lineage	Bacteria → Firmicutes_A → Clostridia → Lachnospirales → Lachnospiraceae → Roseburia	Total connections	319	Host agreement	84.33
PHIST-predicted host lineage	Bacteria → Firmicutes_A → Clostridia → Lachnospirales → Lachnospiraceae → Roseburia → Roseburia hominis	Total connections	1	Host agreement	100

Representative genome content

Select to view: Genome Viewer Functional Annotation

Genome view (completeness: 76.72)

Functional Annotation

Reference	Gene ID	Reference ID	Bit-score	E-value	Information	Category
PHROG	UHGV-0034604_2	phrog_21718	46.7	0.00000000000044	N/A	unknown function
eggNOG-mapper	UHGV-0034604_2	658655.HMPREF0988_00919	150.0	4.2039e-44	N/A	N/A
eggNOG-mapper	UHGV-0034604_3	658655.HMPREF0988_00918	54.3	0.00000000637	N/A	N/A
PHROG	UHGV-0034604_4	phrog_16490	182.6	0	N/A	unknown function
eggNOG-mapper	UHGV-0034604_4	397290.C810_01328	138.0	1.82e-36	N/A	N/A
PHROG	UHGV-0034604_6	phrog_20016	227.8	0	N/A	unknown function
UniRef90	UHGV-0034604_6	UniRef90_A0A285PT46	174.0	0	Tumour necrosis factor-like domain	N/A
eggNOG-mapper	UHGV-0034604_6	397290.C810_05214	236.0	0	N/A	N/A
structural_annotation	UHGV-0034604_6	PF18573,NF033147	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0034604_7	658655.HMPREF0988_00915	118.0	6.57e-30	N/A	N/A
UniRef90	UHGV-0034604_8	UniRef90_UPI00174DD543	63.2	0.00000000000461	CopG family transcriptional regulator	N/A
eggNOG-mapper	UHGV-0034604_8	445971.ANASTE_00673	49.3	0.000000279	N/A	N/A
structural_annotation	UHGV-0034604_8	PF12651,NF041793,COG4710	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_10	phrog_373	98.8	5.9e-29	anti-repressor	transcription regulation
UniRef90	UHGV-0034604_10	UniRef90_UPI001C02FA3A	300.0	0	Rha family transcriptional regulator	N/A
eggNOG-mapper	UHGV-0034604_10	97139.C824_03355	138.0	2.08e-38	Phage regulatory protein	N/A
Pfam	UHGV-0034604_10	PF09669	N/A	N/A	Phage regulatory protein Rha (Phage_pRha)	Phage_pRha
NCBIFam	UHGV-0034604_10	TIGR02681.1	N/A	N/A	phage regulatory protein, Rha family	N/A
COG	UHGV-0034604_10	COG3646	N/A	N/A	Phage regulatory protein Rha	N/A
structural_annotation	UHGV-0034604_10	PF09669,TIGR02681,COG3646	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_11	phrog_1233	46.1	0.00000000000082	N/A	unknown function
eggNOG-mapper	UHGV-0034604_11	658655.HMPREF0988_00914	135.0	3.96e-40	N/A	N/A
structural_annotation	UHGV-0034604_11	PF13058	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_18	phrog_31631	40.8	0.000000000027	N/A	unknown function
eggNOG-mapper	UHGV-0034604_18	658655.HMPREF0988_00903	46.2	0.00000639	N/A	N/A
eggNOG-mapper	UHGV-0034604_20	1304866.K413DRAFT_4686	75.9	1.48e-17	N/A	N/A
eggNOG-mapper	UHGV-0034604_21	742738.HMPREF9460_04058	108.0	6.04e-26	N/A	N/A
eggNOG-mapper	UHGV-0034604_22	658655.HMPREF0988_00895	109.0	8.35e-28	N/A	N/A
structural_annotation	UHGV-0034604_25	PF18895,NF009256	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_30	phrog_25639	60.0	3.1e-17	N/A	unknown function
eggNOG-mapper	UHGV-0034604_30	1282664.H354_06631	46.6	0.00000772	N/A	N/A
structural_annotation	UHGV-0034604_32	PF10694	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_33	phrog_38	139.4	2.70002e-41	terminase large subunit	head and packaging
UniRef90	UHGV-0034604_33	UniRef90_A0A352SH30	1031.0	0	Terminase_6C domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_33	397290.C810_01390	669.0	0	chromosome segregation	N/A
Pfam	UHGV-0034604_33	PF17289	N/A	N/A	Terminase RNaseH-like domain	Terminase_6C
COG	UHGV-0034604_33	COG5410	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0034604_33	PF17289,PF04466,MF_04147,NF033889,COG5410,COG5362	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_34	phrog_36	57.5	2.9e-16	transcriptional regulator	transcription regulation
eggNOG-mapper	UHGV-0034604_34	397290.C810_01391	175.0	0	N/A	N/A
structural_annotation	UHGV-0034604_34	PF02996	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_35	phrog_64	167.6	0	portal protein	head and packaging
UniRef90	UHGV-0034604_35	UniRef90_A0A3R6ASF4	914.0	0	Phage portal protein	N/A
eggNOG-mapper	UHGV-0034604_35	1298920.KI911353_gene2663	457.0	0	Phage portal protein, SPP1 Gp6-like	N/A
Pfam	UHGV-0034604_35	PF05133	N/A	N/A	Phage portal protein, SPP1 Gp6-like	Phage_prot_Gp6
structural_annotation	UHGV-0034604_35	PF05133,MF_04120,TIGR01538,COG5511	N/A	N/A	N/A	N/A
UniRef90	UHGV-0034604_36	UniRef90_R6C0B6	137.0	9.71e-38	Phage capsid scaffolding protein	N/A
PHROG	UHGV-0034604_37	phrog_909	79.1	4.6e-23	major head protein	head and packaging
UniRef90	UHGV-0034604_37	UniRef90_R7BGI8	169.0	0	Phage major capsid protein	N/A
eggNOG-mapper	UHGV-0034604_37	268407.PWYN_15680	49.7	0.00000446	N/A	N/A
PHROG	UHGV-0034604_38	phrog_29	160.6	0	major head protein	head and packaging
UniRef90	UHGV-0034604_38	UniRef90_A0A173UF26	631.0	0	Phage major capsid protein E	N/A
eggNOG-mapper	UHGV-0034604_38	1118054.CAGW01000102_gene4700	162.0	3.08286e-44	Phage major capsid protein E	N/A
Pfam	UHGV-0034604_38	PF03864	N/A	N/A	Phage major capsid protein E	Phage_cap_E
structural_annotation	UHGV-0034604_38	PF03864,MF_04133,NF041162,COG4653	N/A	N/A	N/A	N/A
UniRef90	UHGV-0034604_39	UniRef90_A0A416G2T8	72.4	0.00000000000000511	Rho_N domain-containing protein	N/A
structural_annotation	UHGV-0034604_39	PF21169	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0034604_40	397290.C810_01402	66.2	0.00000000000229	N/A	N/A
PHROG	UHGV-0034604_41	phrog_1863	52.5	0.0000000000000045	N/A	unknown function
eggNOG-mapper	UHGV-0034604_41	1232452.BAIB02000007_gene1606	67.8	0.000000000000365	N/A	N/A
PHROG	UHGV-0034604_42	phrog_18218	136.0	1.10001e-40	N/A	unknown function
UniRef90	UHGV-0034604_42	UniRef90_A0A8D9PGR5	176.0	0	Holin	N/A
eggNOG-mapper	UHGV-0034604_42	411902.CLOBOL_03424	79.0	1.39e-17	N/A	N/A
structural_annotation	UHGV-0034604_42	PF06946	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0034604_43	1298920.KI911353_gene2656	57.0	0.0000000335	N/A	N/A
structural_annotation	UHGV-0034604_43	PF07405,TIGR01563,COG5614	N/A	N/A	N/A	N/A
UniRef90	UHGV-0034604_44	UniRef90_UPI001BBD4500	161.0	0	HK97 gp10 family phage protein	N/A
eggNOG-mapper	UHGV-0034604_44	397290.C810_01411	206.0	0	N/A	N/A
structural_annotation	UHGV-0034604_44	PF17395,TIGR01725,COG5005	N/A	N/A	N/A	N/A
structural_annotation	UHGV-0034604_45	PF05657	N/A	N/A	N/A	N/A
eggNOG-mapper	UHGV-0034604_46	476272.RUMHYD_01968	187.0	0	N/A	N/A
structural_annotation	UHGV-0034604_46	PF16463,TIGR02241,COG5437	N/A	N/A	N/A	N/A
KOfam	UHGV-0034604_49	K07273	178.3	0	acm; lysozyme	N/A
PHROG	UHGV-0034604_49	phrog_291	129.7	2.5e-38	endolysin	lysis
UniRef90	UHGV-0034604_49	UniRef90_A0A1Q6KJN7	677.0	0	LysM domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_49	1235800.C819_00458	211.0	0	Glycosyl hydrolases family 25	N/A
Pfam	UHGV-0034604_49	PF01183	N/A	N/A	Glycosyl hydrolases family 25	Glyco_hydro_25
Pfam	UHGV-0034604_49	PF01476	N/A	N/A	LysM domain	LysM
COG	UHGV-0034604_49	COG3757	N/A	N/A	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	N/A
structural_annotation	UHGV-0034604_49	PF01183,PF01476,TIGR02899,NF007360,COG3757,COG1388	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_50	phrog_1535	160.7	0	tail length tape measure protein	tail
UniRef90	UHGV-0034604_50	UniRef90_A0A173UHS1	283.0	0	Phage-related protein	N/A
eggNOG-mapper	UHGV-0034604_50	1298920.KI911353_gene2649	243.0	0	tape measure	N/A
COG	UHGV-0034604_50	COG3941	N/A	N/A	Phage tail tape-measure protein, controls tail length	N/A
UniRef90	UHGV-0034604_51	UniRef90_A0A395Z832	139.0	1.06e-37	N/A	N/A
eggNOG-mapper	UHGV-0034604_51	697329.Rumal_0454	131.0	5.28e-35	N/A	N/A
Pfam	UHGV-0034604_51	PF11611	N/A	N/A	N/A	DUF4352
structural_annotation	UHGV-0034604_51	PF11611,PF13828,MF_00791,NF003967,COG2967	N/A	N/A	N/A	N/A
UniRef90	UHGV-0034604_52	UniRef90_R7B8I7	87.4	1.2e-21	Ribbon-helix-helix protein CopG family	N/A
eggNOG-mapper	UHGV-0034604_52	663952.SDD27957_09060	49.3	0.000000271	N/A	N/A
Pfam	UHGV-0034604_52	PF12651	N/A	N/A	Ribbon-helix-helix domain	RHH_3
structural_annotation	UHGV-0034604_52	PF12651,NF041793,COG4710	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_55	phrog_463	234.0	0	anti-repressor	transcription regulation
UniRef90	UHGV-0034604_55	UniRef90_UPI0015FAFAAB	312.0	0	ORF6C domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_55	596315.HMPREF0634_0237	164.0	0	BRO family, N-terminal domain protein	N/A
Pfam	UHGV-0034604_55	PF02498	N/A	N/A	BRO family, N-terminal domain	Bro-N
Pfam	UHGV-0034604_55	PF10552	N/A	N/A	ORF6C domain	ORF6C
COG	UHGV-0034604_55	COG3617	N/A	N/A	Prophage antirepressor	N/A
structural_annotation	UHGV-0034604_55	PF10552,PF02498,TIGR02681,COG3617	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_56	phrog_373	113.7	1.7e-33	anti-repressor	transcription regulation
UniRef90	UHGV-0034604_56	UniRef90_A0A2S6HJ41	234.0	0	Phage regulator Rha-like protein	N/A
eggNOG-mapper	UHGV-0034604_56	1235792.C808_03051	128.0	7.98e-35	Phage regulatory protein Rha (Phage_pRha)	N/A
Pfam	UHGV-0034604_56	PF09669	N/A	N/A	Phage regulatory protein Rha (Phage_pRha)	Phage_pRha
NCBIFam	UHGV-0034604_56	TIGR02681.1	N/A	N/A	phage regulatory protein, Rha family	N/A
COG	UHGV-0034604_56	COG3646	N/A	N/A	Phage regulatory protein Rha	N/A
structural_annotation	UHGV-0034604_56	PF02498,TIGR02681,COG3617	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_59	phrog_1194	68.7	7.4e-20	N/A	unknown function
eggNOG-mapper	UHGV-0034604_59	483218.BACPEC_01144	61.6	0.000000000336	N/A	N/A
Pfam	UHGV-0034604_59	PF20458	N/A	N/A	N/A	DUF6711
structural_annotation	UHGV-0034604_59	PF20458,TIGR01633,COG3499	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_60	phrog_18190	590.8	0	N/A	unknown function
UniRef90	UHGV-0034604_60	UniRef90_UPI001C01E293	1165.0	0	tail fiber domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_60	1235790.C805_00089	444.0	0	N/A	N/A
Pfam	UHGV-0034604_60	PF13884	N/A	N/A	Chaperone of endosialidase	Peptidase_S74
structural_annotation	UHGV-0034604_60	PF14594,NF033848,COG3500	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_62	phrog_17196	122.0	7.4e-40	kinase	other
UniRef90	UHGV-0034604_62	UniRef90_A0A3R6GQJ1	437.0	0	Peptidase S74 domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_62	1235790.C805_00090	199.0	0	N/A	N/A
Pfam	UHGV-0034604_62	PF13884	N/A	N/A	Chaperone of endosialidase	Peptidase_S74
PHROG	UHGV-0034604_64	phrog_8	55.6	7.4e-16	transcriptional regulator	transcription regulation
UniRef90	UHGV-0034604_64	UniRef90_A0A1Q9J746	218.0	0	HTH cro/C1-type domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_64	1536772.R70723_06535	64.3	0.000000000245	addiction module antidote protein HigA	N/A
Pfam	UHGV-0034604_64	PF01381	N/A	N/A	Helix-turn-helix	HTH_3
COG	UHGV-0034604_64	COG3093	N/A	N/A	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	N/A
structural_annotation	UHGV-0034604_64	PF12844,NF041951,COG1476	N/A	N/A	N/A	N/A
UniRef90	UHGV-0034604_65	UniRef90_UPI001D13C8FC	73.2	0.0000000000000011	helix-turn-helix domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_65	411474.COPEUT_00689	52.4	0.000000517	sequence-specific DNA binding	N/A
COG	UHGV-0034604_65	COG2944	N/A	N/A	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	N/A
structural_annotation	UHGV-0034604_65	PF01381,NF041951,COG3655	N/A	N/A	N/A	N/A
KOfam	UHGV-0034604_66	K07741	55.8	0.0000000000000015	antB; anti-repressor protein	N/A
PHROG	UHGV-0034604_66	phrog_373	69.6	5.2e-20	anti-repressor	transcription regulation
UniRef90	UHGV-0034604_66	UniRef90_R9KXP0	313.0	0	AntA domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_66	397290.C810_01343	313.0	0	AntA/AntB antirepressor	N/A
Pfam	UHGV-0034604_66	PF08346	N/A	N/A	AntA/AntB antirepressor	AntA
COG	UHGV-0034604_66	COG3561	N/A	N/A	Phage anti-repressor protein Ant	N/A
structural_annotation	UHGV-0034604_66	PF08346,TIGR02681,COG3561	N/A	N/A	N/A	N/A
KOfam	UHGV-0034604_68	K07699	135.0	4.9e-40	spo0A; two-component system, response regulator, stage 0 sporulation protein A	N/A
PHROG	UHGV-0034604_68	phrog_37855	93.6	1.8e-27	N/A	unknown function
UniRef90	UHGV-0034604_68	UniRef90_A0A1Q6KA48	249.0	0	Spo0A_C domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_68	411489.CLOL250_02814	105.0	7.96e-26	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	N/A
Pfam	UHGV-0034604_68	PF08769	N/A	N/A	Sporulation initiation factor Spo0A C terminal	Spo0A_C
COG	UHGV-0034604_68	COG2201	N/A	N/A	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	N/A
structural_annotation	UHGV-0034604_68	PF08769,TIGR02875	N/A	N/A	N/A	N/A
KOfam	UHGV-0034604_70	K08309	45.5	0.0000000000012	slt; soluble lytic murein transglycosylase [EC:4.2.2.-]	N/A
PHROG	UHGV-0034604_70	phrog_19890	101.9	5.4e-30	N/A	unknown function
UniRef90	UHGV-0034604_70	UniRef90_UPI001C014972	302.0	0	transglycosylase SLT domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_70	1410650.JHWL01000003_gene2854	108.0	2.57e-27	lytic transglycosylase activity	N/A
Pfam	UHGV-0034604_70	PF01464	N/A	N/A	Transglycosylase SLT domain	SLT
COG	UHGV-0034604_70	COG0741	N/A	N/A	Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain)	N/A
structural_annotation	UHGV-0034604_70	PF01464,MF_01381,NF011856,COG0741	N/A	N/A	N/A	N/A
KOfam	UHGV-0034604_71	K03111	45.1	1.4e-17	ssb; single-strand DNA-binding protein	N/A
PHROG	UHGV-0034604_71	phrog_26861	138.6	2.79993e-41	N/A	unknown function
UniRef90	UHGV-0034604_71	UniRef90_A0A1Q6KA67	414.0	0	Single-stranded DNA-binding protein	N/A
eggNOG-mapper	UHGV-0034604_71	622312.ROSEINA2194_00317	248.0	0	PFAM single-strand binding protein Primosomal replication protein n	N/A
Pfam	UHGV-0034604_71	PF00436	N/A	N/A	Single-strand binding protein family	SSB
NCBIFam	UHGV-0034604_71	NF004476.0	N/A	N/A	single-stranded DNA-binding protein	N/A
COG	UHGV-0034604_71	COG0629	N/A	N/A	Single-stranded DNA-binding protein	N/A
structural_annotation	UHGV-0034604_71	PF00436,PF13567,MF_00984,NF004476,COG0629	N/A	N/A	N/A	N/A
KOfam	UHGV-0034604_72	K19171	105.5	4.9e-31	dndD; DNA sulfur modification protein DndD	N/A
PHROG	UHGV-0034604_72	phrog_77	242.9	0	SbcC-like subunit of palindrome specific endonuclease	DNA, RNA and nucleotide metabolism
UniRef90	UHGV-0034604_72	UniRef90_A0A1Q6KA53	1147.0	0	AAA_15 domain-containing protein	N/A
eggNOG-mapper	UHGV-0034604_72	1294142.CINTURNW_1008	312.0	0	nuclear chromosome segregation	N/A
PADLOC	UHGV-0034604_72	AAA_15	41.8	0.000000000041	N/A	N/A
Pfam	UHGV-0034604_72	PF13476	N/A	N/A	AAA domain	AAA_23
COG	UHGV-0034604_72	COG1196	N/A	N/A	Chromosome segregation ATPase Smc	N/A
structural_annotation	UHGV-0034604_72	PF02463,MF_00449,NF041034,COG0419	N/A	N/A	N/A	N/A
PHROG	UHGV-0034604_73	phrog_4433	243.9	0	N/A	unknown function
UniRef90	UHGV-0034604_73	UniRef90_A0A6M5C839	115.0	3.8e-29	Putative ADP-ribosyltransferase	N/A
eggNOG-mapper	UHGV-0034604_73	665950.HMPREF1025_01373	165.0	0	regulation of DNA-templated transcription, elongation	N/A
COG	UHGV-0034604_73	COG5164	N/A	N/A	Transcription elongation factor SPT5	N/A

All viral genomes

ID	Representative?	Length (bps)	% GC Content	CheckV Completeness	geNomad Score
UHGV-0034604	Yes	46,025	41	77	1